Gastrointestinal disorders in hyperkinetic movement disorders and ataxia.
Ataxia
BMI
Chorea
Constipation
Dyspepsia
Dysphagia
Dystonia
Gastritis
Gastrointestinal
Gastroparesis
Irritable bowel syndrome
Movement disorder
Myoclonus
Paroxysmal movement disorders
Restless legs syndrome
Sialorrhea
Tardive dyskinesia
Tremor
Weight
Journal
Parkinsonism & related disorders
ISSN: 1873-5126
Titre abrégé: Parkinsonism Relat Disord
Pays: England
ID NLM: 9513583
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
12
12
2020
revised:
24
08
2021
accepted:
08
09
2021
pubmed:
22
9
2021
medline:
12
2
2022
entrez:
21
9
2021
Statut:
ppublish
Résumé
Gastrointestinal (GI) disorders have been thoroughly investigated in hypokinetic disorders such as Parkinson's disease, but much less is known about GI disorders in hyperkinetic movement disorders and ataxia. The aim of this review is to draw attention to the GI disorders that are associated with these movement disorders. References for this systematic review were identified by searches of PubMed through May 2020. Only publications in English were reviewed. Data from 249 articles were critically reviewed, compared, and integrated. The most frequently reported GI symptoms overall in hyperkinetic movement disorders and ataxia are dysphagia, sialorrhea, weight changes, esophago-gastritis, gastroparesis, constipation, diarrhea, and malabsorption. We report in detail on the frequency, characteristics, pathophysiology, and management of GI symptoms in essential tremor, restless legs syndrome, chorea, and spinocerebellar ataxias. The limited available data on GI disorders in dystonias, paroxysmal movement disorders, tardive dyskinesias, myoclonus, and non-SCA ataxias are also summarized. The purpose of our systematic review is to draw attention that, although primarily motor disorders, hyperkinetic movement disorders and ataxia can involve the GI system. Raising awareness about the GI symptom burden in hyperkinetic movement disorders and ataxia could contribute to a new research interest in that field, as well as improved patient care.
Sections du résumé
BACKGROUND
Gastrointestinal (GI) disorders have been thoroughly investigated in hypokinetic disorders such as Parkinson's disease, but much less is known about GI disorders in hyperkinetic movement disorders and ataxia. The aim of this review is to draw attention to the GI disorders that are associated with these movement disorders.
METHODS
References for this systematic review were identified by searches of PubMed through May 2020. Only publications in English were reviewed.
RESULTS
Data from 249 articles were critically reviewed, compared, and integrated. The most frequently reported GI symptoms overall in hyperkinetic movement disorders and ataxia are dysphagia, sialorrhea, weight changes, esophago-gastritis, gastroparesis, constipation, diarrhea, and malabsorption. We report in detail on the frequency, characteristics, pathophysiology, and management of GI symptoms in essential tremor, restless legs syndrome, chorea, and spinocerebellar ataxias. The limited available data on GI disorders in dystonias, paroxysmal movement disorders, tardive dyskinesias, myoclonus, and non-SCA ataxias are also summarized.
CONCLUSION
The purpose of our systematic review is to draw attention that, although primarily motor disorders, hyperkinetic movement disorders and ataxia can involve the GI system. Raising awareness about the GI symptom burden in hyperkinetic movement disorders and ataxia could contribute to a new research interest in that field, as well as improved patient care.
Identifiants
pubmed: 34544654
pii: S1353-8020(21)00334-5
doi: 10.1016/j.parkreldis.2021.09.005
pii:
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
125-133Informations de copyright
Copyright © 2021. Published by Elsevier Ltd.