Primary Pulmonary Mucosa-associated Lymphoid Tissue Lymphoma with the High Expression of IgG4.
IgG4
multiple lung cysts
pulmonary MALT lymphoma
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
01 Apr 2022
01 Apr 2022
Historique:
pubmed:
22
9
2021
medline:
6
4
2022
entrez:
21
9
2021
Statut:
ppublish
Résumé
This is the first report describing primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma with the high expression of IgG4. The histological findings were compatible with the diagnostic criteria for MALT lymphoma and IgG4-related respiratory disease (IgG4-RRD). An unfixed sample for Southern blotting was not obtained since computed tomography findings showed multiple lung cysts, which is rare in patients with MALT lymphoma. However, polymerase chain reaction using paraffin sections showed the clonality of the immunoglobulin heavy chain variable region gene rearrangement, confirming a diagnosis of MALT lymphoma. This is an instructive case in which primary pulmonary MALT lymphoma was histologically compatible with IgG4-RRD.
Identifiants
pubmed: 34544945
doi: 10.2169/internalmedicine.7436-21
pmc: PMC9038459
doi:
Substances chimiques
Immunoglobulin G
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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