Psychotropics and COVID-19: An analysis of safety and prophylaxis.
COVID-19
Prophylaxie
Prophylaxis
Psychotropes
Psychotropics
SARS-CoV-2
Safety
Sécurité clinique
Journal
L'Encephale
ISSN: 0013-7006
Titre abrégé: Encephale
Pays: France
ID NLM: 7505643
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
23
04
2021
accepted:
19
08
2021
pubmed:
23
9
2021
medline:
15
12
2021
entrez:
22
9
2021
Statut:
ppublish
Résumé
The use of psychotropics during the COVID-19 pandemic has raised two questions, in order of importance: first, what changes should be made to pharmacological treatments prescribed to mental health patients? Secondly, are there any positive side effects of these substances against SARS-CoV-2? Our aim was to analyze usage safety of psychotropics during COVID-19; therefore, herein, we have studied: (i) the risk of symptomatic complications of COVID-19 associated with the use of these drugs, notably central nervous system activity depression, QTc interval enlargement and infectious and thromboembolic complications; (ii) the risk of mistaking the iatrogenic impact of psychotropics with COVID-19 symptoms, causing diagnostic error. Moreover, we provided a summary of the different information available today for these risks, categorized by mental health disorder, for the following: schizophrenia, bipolar disorder, anxiety disorder, ADHD, sleep disorders and suicidal risk. The matter of psychoactive substance use during the pandemic is also analyzed in this paper, and guideline websites and publications for psychotropic treatments in the context of COVID-19 are referenced during the text, so that changes on those guidelines and eventual interaction between psychotropics and COVID-19 treatment medication can be reported and studied. Finally, we also provide a literature review of the latest known antiviral properties of psychotropics against SARS-CoV-2 as complementary information.
Identifiants
pubmed: 34548153
pii: S0013-7006(21)00171-8
doi: 10.1016/j.encep.2021.08.002
pmc: PMC8410507
pii:
doi:
Substances chimiques
Psychotropic Drugs
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
564-588Informations de copyright
Copyright © 2021 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.
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