Interactions of polymyxin B with lipopolysaccharide-containing membranes.


Journal

Faraday discussions
ISSN: 1364-5498
Titre abrégé: Faraday Discuss
Pays: England
ID NLM: 9212301

Informations de publication

Date de publication:
24 12 2021
Historique:
pubmed: 23 9 2021
medline: 3 2 2022
entrez: 22 9 2021
Statut: epublish

Résumé

Bacterial resistance to antibiotics constantly remodels the battlefront between infections and antibiotic therapy. Polymyxin B, a cationic peptide with an anti-Gram-negative spectrum of activity is re-entering use as a last resort measure and as an adjuvant. We use fluorescence dequenching to investigate the role of the rough chemotype bacterial lipopolysaccharide from

Identifiants

pubmed: 34550139
doi: 10.1039/d1fd00036e
pmc: PMC8704168
doi:

Substances chimiques

Anti-Bacterial Agents 0
Lipopolysaccharides 0
Polymyxins 0
Polymyxin B J2VZ07J96K

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

317-329

Subventions

Organisme : Medical Research Council
ID : MR/N010477/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/N010426/1
Pays : United Kingdom

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Auteurs

Alice Goode (A)

School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK. boyan.bonev@nottingham.ac.uk.

Vivien Yeh (V)

School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK. boyan.bonev@nottingham.ac.uk.

Boyan B Bonev (BB)

School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK. boyan.bonev@nottingham.ac.uk.

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Classifications MeSH