Highly Efficient Encapsulation of Doxorubicin Hydrochloride in Metal-Organic Frameworks for Synergistic Chemotherapy and Chemodynamic Therapy.
doxorubicin hydrochloride
iron-based metal−organic framework
loading capacity
loading efficiency
Journal
ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670
Informations de publication
Date de publication:
11 10 2021
11 10 2021
Historique:
pubmed:
23
9
2021
medline:
25
2
2023
entrez:
22
9
2021
Statut:
ppublish
Résumé
Iron-based metal-organic frameworks (MOFs) have been reported to have great potential for encapsulating doxorubicin hydrochloride (DOX), which is a frequently used anthracycline anticancer drug. However, developing a facile approach to realize high loading capacity and efficiency as well as controlled release of DOX in MOFs remains a huge challenge. Herein, we synthesized water-stable MIL-101(Fe)-C
Identifiants
pubmed: 34550683
doi: 10.1021/acsbiomaterials.1c00874
doi:
Substances chimiques
Ferric Compounds
0
Metal-Organic Frameworks
0
Doxorubicin
80168379AG
Hydrogen Peroxide
BBX060AN9V
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM