Effectiveness of
Journal
Evidence-based complementary and alternative medicine : eCAM
ISSN: 1741-427X
Titre abrégé: Evid Based Complement Alternat Med
Pays: United States
ID NLM: 101215021
Informations de publication
Date de publication:
2021
2021
Historique:
received:
21
03
2021
revised:
06
08
2021
accepted:
16
08
2021
entrez:
23
9
2021
pubmed:
24
9
2021
medline:
24
9
2021
Statut:
epublish
Résumé
Functional constipation (FC) is a health concern that is prevalent in the pediatric population. It lowers the quality of life and increases the probability of comorbidities. As a complementary modality, herbal medicine has been considered useful in a variety of conditions. Persian medicine (PM) resources mention the This randomized, active-controlled, single-center trial was conducted on 140 children aged between 4 and 10 years with confirmed FC according to Rome III criteria. Participants were randomly assigned to receive either VFS or PEG for four weeks. Independent After four weeks of intervention, 133 individuals (66 in VFS and 67 in the PEG group) were analyzed. Results of both groups demonstrated significant improvement in all measured criteria at the end of the study compared to baseline ( The findings of this investigation indicated that VFS is an effective and relatively safe medication to be used in the treatment of pediatric FC.
Sections du résumé
BACKGROUND
BACKGROUND
Functional constipation (FC) is a health concern that is prevalent in the pediatric population. It lowers the quality of life and increases the probability of comorbidities. As a complementary modality, herbal medicine has been considered useful in a variety of conditions. Persian medicine (PM) resources mention the
METHODS
METHODS
This randomized, active-controlled, single-center trial was conducted on 140 children aged between 4 and 10 years with confirmed FC according to Rome III criteria. Participants were randomly assigned to receive either VFS or PEG for four weeks. Independent
RESULTS
RESULTS
After four weeks of intervention, 133 individuals (66 in VFS and 67 in the PEG group) were analyzed. Results of both groups demonstrated significant improvement in all measured criteria at the end of the study compared to baseline (
CONCLUSION
CONCLUSIONS
The findings of this investigation indicated that VFS is an effective and relatively safe medication to be used in the treatment of pediatric FC.
Identifiants
pubmed: 34552657
doi: 10.1155/2021/9915289
pmc: PMC8452406
doi:
Types de publication
Journal Article
Langues
eng
Pagination
9915289Informations de copyright
Copyright © 2021 Sara Tavassoli et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
Références
Iran J Pediatr. 2015 Apr;25(2):e425
pubmed: 26196006
Gastroenterology. 2006 Apr;130(5):1527-37
pubmed: 16678566
J Res Med Sci. 2016 Nov 02;21:103
pubmed: 28250780
Pediatrics. 2008 Aug;122(2):e446-51
pubmed: 18662934
Behav Res Methods. 2007 May;39(2):175-91
pubmed: 17695343
Best Pract Res Clin Gastroenterol. 2011 Feb;25(1):3-18
pubmed: 21382575
Iran Red Crescent Med J. 2014 Dec 14;16(12):e17511
pubmed: 25763239
J Pediatr Gastroenterol Nutr. 2019 Mar;68(3):318-324
pubmed: 30383579
Paediatr Drugs. 2015 Oct;17(5):349-60
pubmed: 26259965
BMC Complement Altern Med. 2013 Mar 27;13:70
pubmed: 23530615
J Evid Based Complementary Altern Med. 2015 Oct;20(4):287-91
pubmed: 25954025
Aliment Pharmacol Ther. 2001 Jun;15(6):749-63
pubmed: 11380313
J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):10-15
pubmed: 28906317
J Pediatr Gastroenterol Nutr. 2011 Jan;52(1):47-54
pubmed: 20890220
Pediatric Health Med Ther. 2017 Mar 09;8:19-27
pubmed: 29388621
J Gastroenterol Hepatol. 2006 Apr;21(4):638-46
pubmed: 16677147
Gastroenterology. 2017 Jan;152(1):82-91
pubmed: 27650174
Aliment Pharmacol Ther. 2010 May;31(9):938-49
pubmed: 20180788
Curr Drug Discov Technol. 2020;17(5):696-703
pubmed: 31250761
Nat Rev Gastroenterol Hepatol. 2020 Jan;17(1):21-39
pubmed: 31690829
J Strength Cond Res. 2013 Aug;27(8):2323-37
pubmed: 23880657
J Pediatr Gastroenterol Nutr. 2014 Feb;58(2):258-74
pubmed: 24345831
J Neurogastroenterol Motil. 2011 Jan;17(1):35-47
pubmed: 21369490
Eur J Pediatr. 2014 Nov;173(11):1413-28
pubmed: 24782030
Avicenna J Phytomed. 2016 Jul-Aug;6(4):434-41
pubmed: 27516984
Lipids Health Dis. 2012 Jan 10;11:6
pubmed: 22233644
J Pediatr. 2009 Feb;154(2):258-62
pubmed: 18822430