A non-cytotoxic regimen of decitabine to treat refractory T-cell large granular lymphocytic leukemia.

T‐cell large granular lymphocytic leukemia decitabine frail patients non‐cytotoxic regimen

Journal

Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 05 05 2021
revised: 04 06 2021
accepted: 14 06 2021
entrez: 23 9 2021
pubmed: 24 9 2021
medline: 24 9 2021
Statut: epublish

Résumé

We report on a novel, successful, non-cytotoxic therapy to treat multiply-refractory T-LGL in an elderly patient.

Identifiants

pubmed: 34552731
doi: 10.1002/ccr3.4533
pii: CCR34533
pmc: PMC8443408
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e04533

Informations de copyright

© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Déclaration de conflit d'intérêts

YS has equity in EpiDestiny. There is no financial and research support. YS received intellectual property—patents around tetrahydrouridine, decitabine, and 5‐azacytidine (US 9,259,469 B2; US 9,265,785 B2; US 9,895,391 B2) and cancer differentiation therapy (US 9,926,316 B2).

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Auteurs

Misam Zawit (M)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.

Carmelo Gurnari (C)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.
Department of Biomedicine and Prevention & Ph.D in Immunology, Molecular Medicine and Applied Biotechnology University of Rome Tor Vergata Rome Italy.

Simona Pagliuca (S)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.
Université de Paris Paris France.

Hassan Awada (H)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.

Jaroslaw P Maciejewski (JP)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.

Yogen Saunthararajah (Y)

Translational Hematology and Oncology Research Department Taussig Cancer Center Cleveland Clinic Cleveland OH USA.

Classifications MeSH