"Internal and External Combined" Nonradiative Decay-Based Nanoagents for Photoacoustic Image-Guided Highly Efficient Photothermal Therapy.
Animals
Antineoplastic Agents
/ chemical synthesis
Cell Line, Tumor
Combined Modality Therapy
Density Functional Theory
Female
Heterocyclic Compounds, 4 or More Rings
/ chemical synthesis
Humans
Indans
/ chemical synthesis
Infrared Rays
Mice, Inbred BALB C
Models, Chemical
Nanoparticles
/ chemistry
Neoplasms
/ diagnostic imaging
Photoacoustic Techniques
Photothermal Therapy
Theranostic Nanomedicine
/ methods
dark excited states
organic nanoagents
photoacoustic imaging
photothermal tumor ablation
rotor motion
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
06 Oct 2021
06 Oct 2021
Historique:
pubmed:
25
9
2021
medline:
1
2
2022
entrez:
24
9
2021
Statut:
ppublish
Résumé
Rational manipulation of nonradiative decay channels is of crucial significance to improve photothermal conversion efficiency (PCE) and design photothermal agents. We first used the "internal and external combined" nonradiative decay strategy to enhance PCE. Specifically, organic IR-Y6 NPs with strong NIR absorption and high molar extinction coefficient were prepared and characterized. By means of TD-DFT calculations and fs-TA spectroscopy, the dual nonradiative decay channels composed of the free rotor (external strategy) and ultrafast dark excited states (DESs) between S
Identifiants
pubmed: 34559529
doi: 10.1021/acsami.1c14020
doi:
Substances chimiques
Antineoplastic Agents
0
Heterocyclic Compounds, 4 or More Rings
0
Indans
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM