Assessment of Impaired Cerebrovascular Reactivity in Chronic Cerebral Ischemia using Intravoxel Incoherent Motion Magnetic Resonance Imaging.

Brain Ischemia / diagnostic imaging Humans Magnetic Resonance Imaging Motion
Cerebral blood volume Cerebrovascular reactivity Chronic cerebral ischemia Intravoxel incoherent motion Magnetic resonance imaging Perfusion fraction

Journal

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
ISSN: 1532-8511
Titre abrégé: J Stroke Cerebrovasc Dis
Pays: United States
ID NLM: 9111633

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 25 02 2021
revised: 10 08 2021
accepted: 04 09 2021
pubmed: 26 9 2021
medline: 9 2 2022
entrez: 25 9 2021
Statut: ppublish

Résumé

The severity of chronic cerebral ischemia can be assessed using cerebrovascular reactivity (CVR) to acetazolamide (ACZ) challenge, which is measured by single-photon emission computed tomography (SPECT); however, this is an invasive method. We investigated whether intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) can assess impaired CVR in preoperative patients with chronic cerebral ischemia and compared it to SPECT-CVR. Forty-seven patients with unilateral cervical carotid artery stenosis underwent diffusion-weighted MRI with 11 b-values in the range of 0-800 s/mm The IVIM-f and D values in the affected side were significantly higher than those in the unaffected side (median: 7.74% vs. 7.45%, p = 0.027; 0.816 vs. 0.801 10 The IVIM perfusion parameter, f, can noninvasively assess impaired CVR with high sensitivity and specificity in patients with unilateral cervical carotid artery stenosis.

Sections du résumé

BACKGROUND BACKGROUND
The severity of chronic cerebral ischemia can be assessed using cerebrovascular reactivity (CVR) to acetazolamide (ACZ) challenge, which is measured by single-photon emission computed tomography (SPECT); however, this is an invasive method. We investigated whether intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) can assess impaired CVR in preoperative patients with chronic cerebral ischemia and compared it to SPECT-CVR.
METHODS METHODS
Forty-seven patients with unilateral cervical carotid artery stenosis underwent diffusion-weighted MRI with 11 b-values in the range of 0-800 s/mm
RESULTS RESULTS
The IVIM-f and D values in the affected side were significantly higher than those in the unaffected side (median: 7.74% vs. 7.45%, p = 0.027; 0.816 vs. 0.801 10
CONCLUSION CONCLUSIONS
The IVIM perfusion parameter, f, can noninvasively assess impaired CVR with high sensitivity and specificity in patients with unilateral cervical carotid artery stenosis.

Identifiants

DOI: 10.1016/j.jstrokecerebrovasdis.2021.106107 PMID: 34562793
pubmed: 34562793
pii: S1052-3057(21)00512-7
doi: 10.1016/j.jstrokecerebrovasdis.2021.106107
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106107

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None

Auteurs

Ikuko Uwano (I)

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 1-1-1 Idai-dori, Yahaba, Iwate 028-3694, Japan. Electronic address: uwano@iwate-med.ac.jp.

Masakazu Kobayashi (M)

Department of Neurosurgery, Iwate Medical University, Yahaba, Iwate, Japan.

Kengo Setta (K)

Department of Neurosurgery, Iwate Medical University, Yahaba, Iwate, Japan.

Kuniaki Ogasawara (K)

Department of Neurosurgery, Iwate Medical University, Yahaba, Iwate, Japan.

Fumio Yamashita (F)

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 1-1-1 Idai-dori, Yahaba, Iwate 028-3694, Japan.

Futoshi Mori (F)

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 1-1-1 Idai-dori, Yahaba, Iwate 028-3694, Japan.

Tsuyoshi Matsuda (T)

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 1-1-1 Idai-dori, Yahaba, Iwate 028-3694, Japan.

Makoto Sasaki (M)

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, 1-1-1 Idai-dori, Yahaba, Iwate 028-3694, Japan.

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Classifications MeSH

questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Angiopathies intracrâniennes › Encéphalopathie ischémique › Assessment of Impaired Cerebrovascular...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Assessment of Impaired Cerebrovascular...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Assessment of Impaired Cerebrovascular...
questionsmedicales.fr › Phénomènes physiques › Déplacement › Assessment of Impaired Cerebrovascular...