Red Blood Cell Proteasome in Beta-Thalassemia Trait: Topology of Activity and Networking in Blood Bank Conditions.
activity
beta thalassemia trait
interactome
membrane localization
proteasome
proteostasis
red blood cell
regulation
storage
Journal
Membranes
ISSN: 2077-0375
Titre abrégé: Membranes (Basel)
Pays: Switzerland
ID NLM: 101577807
Informations de publication
Date de publication:
17 Sep 2021
17 Sep 2021
Historique:
received:
29
07
2021
revised:
09
09
2021
accepted:
13
09
2021
entrez:
26
9
2021
pubmed:
27
9
2021
medline:
27
9
2021
Statut:
epublish
Résumé
Proteasomes are multi-catalytic complexes with important roles in protein control. Their activity in stored red blood cells (RBCs) is affected by both storage time and the donor's characteristics. However, apart from their abundancy in the membrane proteome, not much is known about their topology, activity, and networking during the storage of RBCs from beta-thalassemia trait donors (βThal
Identifiants
pubmed: 34564533
pii: membranes11090716
doi: 10.3390/membranes11090716
pmc: PMC8466122
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL146442
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL148151
Pays : United States
Organisme : NHLBI NIH HHS
ID : R21 HL150032
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL149714
Pays : United States
Organisme : Hellenic Foundation for Research and Innovation (HFRI) and the General Secretariat for Research and Innovation (GSRI)
ID : 2032
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