Novel Methods and Approaches for Safety Evaluation of Nanoparticle Formulations: A Focus Towards
in vitro assay
nanomedicine
nanoparticles
nanotechnology
nanotoxicity assessment
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2021
2021
Historique:
received:
30
09
2020
accepted:
05
08
2021
entrez:
27
9
2021
pubmed:
28
9
2021
medline:
28
9
2021
Statut:
epublish
Résumé
Nanotoxicology is an emerging field employed in the assessment of unintentional hazardous effects produced by nanoparticles (NPs) impacting human health and the environment. The nanotoxicity affects the range between induction of cellular stress and cytotoxicity. The reasons so far reported for these toxicological effects are due to their variable sizes with high surface areas, shape, charge, and physicochemical properties, which upon interaction with the biological components may influence their functioning and result in adverse outcomes (AO). Thus, understanding the risk produced by these materials now is an important safety concern for the development of nanotechnology and nanomedicine. Since the time nanotoxicology has evolved, the methods employed have been majorly relied on
Identifiants
pubmed: 34566630
doi: 10.3389/fphar.2021.612659
pii: 612659
pmc: PMC8458898
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
612659Informations de copyright
Copyright © 2021 Tirumala, Anchi, Raja, Rachamalla and Godugu.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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