The role of diffusion tensor imaging of the liver in children with autoimmune hepatitis.

MR imaging autoimmune hepatitis diffusion fibrosis hepatic

Journal

Polish journal of radiology
ISSN: 1733-134X
Titre abrégé: Pol J Radiol
Pays: Poland
ID NLM: 101175532

Informations de publication

Date de publication:
2021
Historique:
received: 01 01 2021
accepted: 15 04 2021
entrez: 27 9 2021
pubmed: 28 9 2021
medline: 28 9 2021
Statut: epublish

Résumé

To evaluate the role of diffusion tensor imaging (DTI) of the liver in children with autoimmune hepatitis (AIH). A prospective study was done on 42 children with AIH (30 girls and 12 boys, with a mean age of 13 years) and 20 age- and sex-matched healthy control children. They underwent DTI of the liver and laboratory tests. Liver biopsy was done for the patients. The mean diffusivity (MD) and fractional anisotropy (FA) of the liver were calculated and correlated with the pathological results. The mean MD and FA of the liver in children with AIH were 1.42 ± 0.06 × 10 We concluded that DTI parameters can help to diagnose AIH, detect its phenotyping, and give clues as to the presence of associated overlap syndrome.

Identifiants

pubmed: 34567291
doi: 10.5114/pjr.2021.108171
pii: 44840
pmc: PMC8449556
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e461-e467

Informations de copyright

© Pol J Radiol 2021.

Déclaration de conflit d'intérêts

The authors report no conflict of interest.

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Auteurs

Ahmed Abdel Khalek Abdel Razek (AAKA)

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Ahmed Abdalla (A)

Department of Paediatrics, Paediatric University Hospital, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Ahmed Megahed (A)

Department of Paediatrics, Paediatric University Hospital, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Mohamed Elsayed Ahmed (ME)

Department of Paediatrics, Paediatric University Hospital, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Suzy Abd ElMabood (SA)

Department of Paediatrics, Paediatric University Hospital, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Rihame Abdel Wahab (RA)

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Classifications MeSH