Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells.

Culture components Differentiation methods Induced pluripotent stem cells Mesenchymal stem cell markers Mesenchymal stem cells Mesenchymal stem cells derived from induced pluripotent stem cells

Journal

World journal of stem cells

ISSN: 1948-0210

Titre abrégé: World J Stem Cells

Pays: United States

ID NLM: 101535826

Informations de publication

Date de publication:
26 Aug 2021

Historique:

received: 28 02 2021

revised: 03 05 2021

accepted: 14 07 2021

entrez: 27 9 2021

pubmed: 28 9 2021

medline: 28 9 2021

Statut: ppublish

Résumé

Mesenchymal stem cells (MSCs) have received significant attention in recent years due to their large potential for cell therapy. Indeed, they secrete a wide variety of immunomodulatory factors of interest for the treatment of immune-related disorders and inflammatory diseases. MSCs can be extracted from multiple tissues of the human body. However, several factors may restrict their use for clinical applications: the requirement of invasive procedures for their isolation, their limited numbers, and their heterogeneity according to the tissue of origin or donor. In addition, MSCs often present early signs of replicative senescence limiting their expansion

Identifiants

DOI: 10.4252/wjsc.v13.i8.1094 PMID: 34567428 PMC: PMC8422924

pubmed: 34567428

doi: 10.4252/wjsc.v13.i8.1094

pmc: PMC8422924

doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1094-1111

Informations de copyright

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors declare that they have no competing interests.

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