COVID 19 pandemic: Effect on management of patients with breast cancer; single center retrospective cohort study.
Breast cancer
Breast conservation treatment
COVID-19
Modified radical mastectomy
Journal
International journal of surgery open
ISSN: 2405-8572
Titre abrégé: Int J Surg Open
Pays: England
ID NLM: 101729980
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
15
07
2021
revised:
04
08
2021
accepted:
05
08
2021
entrez:
27
9
2021
pubmed:
28
9
2021
medline:
28
9
2021
Statut:
ppublish
Résumé
(SARS-COV-2) infection, led to a pandemic affecting many countries, resulting in hospitals diverting most of their resources to fight the pandemic. Breast cancer, already a healthcare dilemma, is also affected in this scenario. Our aim was to find out the impact of COVID-19 on presentation of breast cancer stage and its effects on overall onco-surgical management. This cohort single-centered retrospective review was carried out at our hospital, over a period of 18 months. Females with known breast cancer were included in the study. Data was collected on performas by a single researcher. Effect of COVID pandemic on presentation stage and its impact on overall management was studied. SPSS 23.0 used for data analysis. A 95% CI was used. Descriptive statistics were presented as range/means. Categorical data was analyzed by Fisher exact test, Out of 87 patients presenting with suspicious lump, 69 who had malignancy on histo-pathology were included in study. Twelve out of 69 were COVID positive. Sixty patients presented with advanced stage (≥stage 2b) out of which 21 underwent upstaging of disease due to delay in presentation/management. We found that 9 out of 12 (majority) Covid positive patients had disease upstaging. Overall main reason for delay in presentation was found to be unawareness of disease. We concluded that COVID-19 pandemic had no impact on presentation delay, breast cancer management/treatment and disease upstaging as compared to figures available for our population before the pandemic. However, our study showed significant correlation between disease upstaging and COVID status. This led us to reconsider our preformed protocols for COVID positive breast cancer patients. Our results can be used by future researchers to investigate if COVID itself can contributes in patho-physiology of upstaging in breast cancer or not.
Sections du résumé
BACKGROUND
BACKGROUND
(SARS-COV-2) infection, led to a pandemic affecting many countries, resulting in hospitals diverting most of their resources to fight the pandemic. Breast cancer, already a healthcare dilemma, is also affected in this scenario. Our aim was to find out the impact of COVID-19 on presentation of breast cancer stage and its effects on overall onco-surgical management.
METHODS
METHODS
This cohort single-centered retrospective review was carried out at our hospital, over a period of 18 months. Females with known breast cancer were included in the study. Data was collected on performas by a single researcher. Effect of COVID pandemic on presentation stage and its impact on overall management was studied. SPSS 23.0 used for data analysis. A 95% CI was used. Descriptive statistics were presented as range/means. Categorical data was analyzed by Fisher exact test,
RESULTS
RESULTS
Out of 87 patients presenting with suspicious lump, 69 who had malignancy on histo-pathology were included in study. Twelve out of 69 were COVID positive. Sixty patients presented with advanced stage (≥stage 2b) out of which 21 underwent upstaging of disease due to delay in presentation/management. We found that 9 out of 12 (majority) Covid positive patients had disease upstaging. Overall main reason for delay in presentation was found to be unawareness of disease.
CONCLUSION
CONCLUSIONS
We concluded that COVID-19 pandemic had no impact on presentation delay, breast cancer management/treatment and disease upstaging as compared to figures available for our population before the pandemic. However, our study showed significant correlation between disease upstaging and COVID status. This led us to reconsider our preformed protocols for COVID positive breast cancer patients. Our results can be used by future researchers to investigate if COVID itself can contributes in patho-physiology of upstaging in breast cancer or not.
Identifiants
pubmed: 34568622
doi: 10.1016/j.ijso.2021.100386
pii: S2405-8572(21)00077-2
pmc: PMC8359567
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100386Informations de copyright
© 2021 The Author(s).
Références
J Pak Med Assoc. 2002 Mar;52(3):100-4
pubmed: 12071063
Cancer. 2014 Jan 1;120(1):20-5
pubmed: 24347383
Public Health. 2001 May;115(3):173-4
pubmed: 11429711
Lancet. 2020 Apr 25;395(10233):1382-1393
pubmed: 32277878
Future Oncol. 2020 Nov;16(31):2551-2567
pubmed: 32715776
Glob Public Health. 2015;10(3):331-44
pubmed: 25443995
Chin J Cancer Res. 2015 Jun;27(3):288-93
pubmed: 26157325
Asian Pac J Cancer Prev. 2015;16(1):377-80
pubmed: 25640384
Br J Cancer. 2002 May 6;86(9):1373-8
pubmed: 11986766
J Psychosom Res. 2005 Apr;58(4):321-6
pubmed: 15992567
N Engl J Med. 2020 May 14;382(20):1873-1875
pubmed: 32187459
Br J Cancer. 2009 Dec 3;101 Suppl 2:S92-S101
pubmed: 19956172
J Gen Intern Med. 2020 May;35(5):1545-1549
pubmed: 32133578
Fam Pract. 2015 Oct;32(5):568-77
pubmed: 26099812
Lancet Oncol. 2020 Mar;21(3):335-337
pubmed: 32066541
Breast Cancer Res. 2020 May 28;22(1):55
pubmed: 32460829
JCO Glob Oncol. 2020 Jun;6:873-883
pubmed: 32579484
Int J Surg. 2019 Dec;72:156-165
pubmed: 31704426
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Cancer Manag Res. 2019 Jan 29;11:1087-1096
pubmed: 30774437
Br J Surg. 2013 Dec;100(13):1756-63
pubmed: 24227361
Radiology. 2011 Jul;260(1):119-28
pubmed: 21493791
Obstet Gynecol Int. 2016;2016:4840762
pubmed: 27882055