NDEx: Accessing Network Models and Streamlining Network Biology Workflows.

Cytoscape JavaScript NDEx R REST API enrichment analysis neighborhood query network biology network models pathway python subnetwork systems biology

Journal

Current protocols
ISSN: 2691-1299
Titre abrégé: Curr Protoc
Pays: United States
ID NLM: 101773894

Informations de publication

Date de publication:
Sep 2021
Historique:
entrez: 27 9 2021
pubmed: 28 9 2021
medline: 30 9 2021
Statut: ppublish

Résumé

NDEx, the Network Data Exchange (https://www.ndexbio.org) is a web-based resource where users can find, store, share and publish network models of any type and size. NDEx is integrated with Cytoscape, the widely used desktop application for network analysis and visualization. NDEx and Cytoscape are the pillars of the Cytoscape Ecosystem, a diverse environment of resources, tools, applications and services for network biology workflows. In this article, we introduce researchers to NDEx and highlight how it can simplify common tasks in network biology workflows as well as streamline publication and access to). Finally, we show how NDEx can be used programmatically via Python with the 'ndex2' client library, and point readers to additional examples for other popular programming languages such as JavaScript and R. © 2021 The Authors. Current Protocols published by Wiley Periodicals LLC. Basic Protocol 1: Getting started with NDEx Basic Protocol 2: Using NDEx and Cytoscape in a publication-oriented workflow Basic Protocol 3: Manipulating networks in NDEx via Python.

Identifiants

pubmed: 34570431
doi: 10.1002/cpz1.258
pmc: PMC8544027
mid: NIHMS1740024
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e258

Subventions

Organisme : NIGMS NIH HHS
ID : P41 GM103504
Pays : United States
Organisme : NCI NIH HHS
ID : U24 CA184427
Pays : United States

Informations de copyright

© 2021 The Authors. Current Protocols published by Wiley Periodicals LLC.

Auteurs

Rudolf T Pillich (RT)

School of Medicine, University of California San Diego, La Jolla, California.

Jing Chen (J)

School of Medicine, University of California San Diego, La Jolla, California.

Christopher Churas (C)

School of Medicine, University of California San Diego, La Jolla, California.

Sophie Liu (S)

School of Medicine, University of California San Diego, La Jolla, California.

Keiichiro Ono (K)

School of Medicine, University of California San Diego, La Jolla, California.

David Otasek (D)

School of Medicine, University of California San Diego, La Jolla, California.

Dexter Pratt (D)

School of Medicine, University of California San Diego, La Jolla, California.

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