Tick gut barriers impacting tick-microbe interactions and pathogen persistence.
Borrelia burgdorferi
Ixodes ticks
arthropod vectors
gut barrier
Journal
Molecular microbiology
ISSN: 1365-2958
Titre abrégé: Mol Microbiol
Pays: England
ID NLM: 8712028
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
21
09
2021
accepted:
23
09
2021
pubmed:
28
9
2021
medline:
27
1
2022
entrez:
27
9
2021
Statut:
ppublish
Résumé
Ticks are regarded as one of the most ancient, unique, and highly evolved ectoparasites. They can parasitize diverse vertebrates and transmit a number of widespread infections. Once acquired from infected hosts, many tick-borne pathogens, like Borrelia burgdorferi, are confined within the tick gut lumen and are surrounded by discrete gut barriers. Such barriers include the peritrophic membrane (PM) and the dityrosine network (DTN), which are in close contact with resident microbiota and invading pathogens, influencing their survival within the vector. Herein, we review our current state of knowledge about tick-microbe interactions involving the PM and DTN structures. As a model, we will focus on Ixodes ticks, their microbiome, and the pathogen of Lyme disease. We will address the most salient findings on the structural and physiological roles of these Ixodes gut barriers on microbial interactions, with a comparison to analogous functions in other model vectors, such as mosquitoes. We will distill how this information could be leveraged towards a better understanding of the basic mechanisms of gut biology and tick-microbial interactions, which could contribute to potential therapeutic strategies in response to ticks and tick-borne infections.
Identifiants
pubmed: 34570926
doi: 10.1111/mmi.14822
pmc: PMC8599643
mid: NIHMS1743316
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1241-1248Subventions
Organisme : NIAID NIH HHS
ID : R01 AI116620
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI080615
Pays : United States
Organisme : NIAID NIH HHS
ID : P01 AI138949
Pays : United States
Informations de copyright
© 2021 John Wiley & Sons Ltd.
Références
PLoS Pathog. 2015 Oct 27;11(10):e1005244
pubmed: 26506243
Exp Cell Res. 2002 Feb 15;273(2):187-96
pubmed: 11822874
Science. 2005 Nov 4;310(5749):847-50
pubmed: 16272120
Insect Biochem Mol Biol. 2002 May;32(5):517-23
pubmed: 11891128
Philos Trans R Soc Lond B Biol Sci. 2005 Dec 29;360(1464):2301-8
pubmed: 16321800
PLoS One. 2013 Oct 17;8(10):e78376
pubmed: 24147133
J Biol Chem. 2015 Jul 3;290(27):16490-501
pubmed: 25991725
FEBS Lett. 2004 Oct 22;576(3):331-5
pubmed: 15498557
Arch Insect Biochem Physiol. 1991;17(2-3):157-68
pubmed: 1802031
J Insect Physiol. 1977;23(2):241-6
pubmed: 323371
J Insect Physiol. 2019 Aug - Sep;117:103898
pubmed: 31211963
J Virol. 2007 Apr;81(8):4235-43
pubmed: 17251284
Vector Borne Zoonotic Dis. 2008 Oct;8(5):701-12
pubmed: 18627241
Parasitology. 1997 Oct;115 ( Pt 4):359-69
pubmed: 9364562
Nat Immunol. 2009 Sep;10(9):949-57
pubmed: 19668222
Nat Rev Microbiol. 2013 Sep;11(9):615-26
pubmed: 23893105
PLoS Pathog. 2017 May 17;13(5):e1006391
pubmed: 28545061
J Gen Virol. 2009 Aug;90(Pt 8):1781-1794
pubmed: 19420159
Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6977-82
pubmed: 9192677
Cell Microbiol. 2021 Feb;23(2):e13275
pubmed: 33006213
Emerg Infect Dis. 2021 Feb;27(2):616-619
pubmed: 33496229
Euro Surveill. 2018 Nov;23(45):
pubmed: 30424829
J Insect Physiol. 2008 Oct-Nov;54(10-11):1413-22
pubmed: 18761346
Nat Commun. 2016 Feb 09;7:10507
pubmed: 26856261
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6961-6
pubmed: 27185908
Insect Biochem Mol Biol. 1999 Feb;29(2):87-101
pubmed: 10196732
Science. 2010 Mar 26;327(5973):1644-8
pubmed: 20223948
Cell Tissue Res. 1982;221(3):471-81
pubmed: 7055834
Nat Rev Microbiol. 2012 Jan 09;10(2):87-99
pubmed: 22230951
FEBS J. 2008 Jul;275(13):3249-77
pubmed: 18513324
Cell Host Microbe. 2014 Jan 15;15(1):58-71
pubmed: 24439898
J Biol Chem. 2005 Aug 26;280(34):30046-54
pubmed: 15972824
Wien Klin Wochenschr. 2019 May 6;:
pubmed: 31062185
Insect Biochem Mol Biol. 2004 Mar;34(3):291-304
pubmed: 14871625
Infect Immun. 2001 Jun;69(6):4048-54
pubmed: 11349075
Am J Trop Med Hyg. 1990 Apr;42(4):352-7
pubmed: 2331043
Parasit Vectors. 2018 Jan 4;11(1):12
pubmed: 29301588
J Biol Chem. 1992 Apr 25;267(12):7959-62
pubmed: 1569052
Parasite Immunol. 2021 May;43(5):e12813
pubmed: 33314216
Clin Infect Dis. 2001 Mar 15;32(6):897-928
pubmed: 11247714
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15966-71
pubmed: 21896728
Crit Rev Biochem Mol Biol. 1992;27(1-2):57-92
pubmed: 1727693
Ticks Tick Borne Dis. 2018 Mar;9(3):535-542
pubmed: 29398603
Annu Rev Entomol. 1997;42:525-50
pubmed: 15012322
Parasitol Res. 1991;77(7):635-41
pubmed: 1792236
Virology. 1988 Nov;167(1):242-50
pubmed: 3055665
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E781-E790
pubmed: 28096373
FEBS Lett. 1988 Jun 6;233(1):74-8
pubmed: 3133245
Cell. 2020 Sep 3;182(5):1328-1340.e13
pubmed: 32814014
J Cell Biol. 2001 Aug 20;154(4):879-91
pubmed: 11514595
Front Cell Infect Microbiol. 2017 Apr 07;7:114
pubmed: 28439499
Insect Sci. 2016 Oct;23(5):656-74
pubmed: 25846407
J Biol Chem. 2014 May 2;289(18):12813-22
pubmed: 24662290
Infect Immun. 2001 Jun;69(6):4041-7
pubmed: 11349074
J Clin Microbiol. 1987 Mar;25(3):557-8
pubmed: 3571459
Arch Insect Biochem Physiol. 2007 Jan;64(1):1-18
pubmed: 17167750