Rates of neuromuscular excitation during cycling in Parkinson's disease compared to healthy young and older adults.
Aging
Cycling
Mobility
Parkinson's disease
Rate of EMG rise
Journal
Clinical biomechanics (Bristol, Avon)
ISSN: 1879-1271
Titre abrégé: Clin Biomech (Bristol, Avon)
Pays: England
ID NLM: 8611877
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
03
05
2021
revised:
08
09
2021
accepted:
14
09
2021
pubmed:
28
9
2021
medline:
27
1
2022
entrez:
27
9
2021
Statut:
ppublish
Résumé
Bradykinesia affects mobility in some people with Parkinson's. Fall risk makes the neural control of maximal speed ambulatory movements difficult to study in Parkinson's. Stationary recumbent bicycling favors the use of electromyography at high movement speeds, and may better reveal neuromuscular rate limiters. Subjects were 18 adults with Parkinson's, 14 older adults and 14 young adults. Electromyograms were recorded from two muscles during stationary recumbent bicycling at 60, 80, 100, 120 RPM and peak voluntary cadence. Rate of electromyogram rise was calculated. Subjects performed the timed up and go and four square step test. Parkinson's sub-groups were formed based on whether they could pedal ≥120 RPM. Mixed models were used to compare groups and spearman's correlations quantified relationships. Eight people with Parkinson's and four older adults could not complete the 120 RPM condition. Faster people with Parkinson's (n = 10) had greater maximum cadence (F = 42.85, P < 0.05), higher rates of electromyogram rise in both muscles (F > 16.9, P < 0.05), and faster mobility test times (F > 6.5, P < 0.05) than slower people with Parkinson's (n = 8). In Parkinson's, correlations between vastus lateralis rate of electromyogram rise and four square step test (ρ = -0.62), timed up and go (ρ = -0.53), and peak cadence (ρ = 0.76) were significant (all P < 0.05). People with Parkinson's with slower peak pedaling cadence had slower mobility performance and lower vastus lateralis excitation rates at higher cadences. Vastus lateralis excitation rates had moderate to strong relationships with peak cadence and mobility. Exercise interventions may seek to improve peak cadence or excitation rates in people with Parkinson's.
Sections du résumé
BACKGROUND
Bradykinesia affects mobility in some people with Parkinson's. Fall risk makes the neural control of maximal speed ambulatory movements difficult to study in Parkinson's. Stationary recumbent bicycling favors the use of electromyography at high movement speeds, and may better reveal neuromuscular rate limiters.
METHODS
Subjects were 18 adults with Parkinson's, 14 older adults and 14 young adults. Electromyograms were recorded from two muscles during stationary recumbent bicycling at 60, 80, 100, 120 RPM and peak voluntary cadence. Rate of electromyogram rise was calculated. Subjects performed the timed up and go and four square step test. Parkinson's sub-groups were formed based on whether they could pedal ≥120 RPM. Mixed models were used to compare groups and spearman's correlations quantified relationships.
FINDINGS
Eight people with Parkinson's and four older adults could not complete the 120 RPM condition. Faster people with Parkinson's (n = 10) had greater maximum cadence (F = 42.85, P < 0.05), higher rates of electromyogram rise in both muscles (F > 16.9, P < 0.05), and faster mobility test times (F > 6.5, P < 0.05) than slower people with Parkinson's (n = 8). In Parkinson's, correlations between vastus lateralis rate of electromyogram rise and four square step test (ρ = -0.62), timed up and go (ρ = -0.53), and peak cadence (ρ = 0.76) were significant (all P < 0.05).
INTERPRETATION
People with Parkinson's with slower peak pedaling cadence had slower mobility performance and lower vastus lateralis excitation rates at higher cadences. Vastus lateralis excitation rates had moderate to strong relationships with peak cadence and mobility. Exercise interventions may seek to improve peak cadence or excitation rates in people with Parkinson's.
Identifiants
pubmed: 34571487
pii: S0268-0033(21)00218-7
doi: 10.1016/j.clinbiomech.2021.105488
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
105488Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.