Assessment and Validation of
Alzheimer Disease
/ drug therapy
Amyloid beta-Peptides
/ metabolism
Animals
Animals, Genetically Modified
/ physiology
Caenorhabditis elegans
/ drug effects
Chemotaxis
Neuroprotective Agents
/ pharmacology
Oxidative Stress
/ drug effects
Reactive Oxygen Species
/ metabolism
Tylenchoidea
/ drug effects
Alzheimer’s disease
Caenorhabditis elegans
Globodera pallida
amyloid-β
in vivo model
oxidative stress
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
19 09 2021
19 09 2021
Historique:
received:
26
07
2021
revised:
01
09
2021
accepted:
11
09
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
23
11
2021
Statut:
epublish
Résumé
Whole transgenic or non-transgenic organism model systems allow the screening of pharmacological compounds for protective actions in Alzheimer's disease (AD). In this study, a plant parasitic nematode, We demonstrated that: (i)
Sections du résumé
BACKGROUND
Whole transgenic or non-transgenic organism model systems allow the screening of pharmacological compounds for protective actions in Alzheimer's disease (AD).
AIM
In this study, a plant parasitic nematode,
RESULTS
We demonstrated that: (i)
Identifiants
pubmed: 34572130
pii: cells10092481
doi: 10.3390/cells10092481
pmc: PMC8465914
pii:
doi:
Substances chimiques
Amyloid beta-Peptides
0
Neuroprotective Agents
0
Reactive Oxygen Species
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : US-Ireland Health and Social Care NI
ID : HSC R&DST/5460/2018
Organisme : Medical Research Council
ID : CIC-CD1718-CIC25
Pays : United Kingdom
Organisme : InvestNI
ID : RD101427 11-01-17-008
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