Incidence, Risk Factors and Impact on Clinical Outcomes of Bloodstream Infections in Patients Hospitalised with COVID-19: A Prospective Cohort Study.
COVID-19
antimicrobial stewardship
bacterial super-infections
bloodstream infections
corticosteroid therapy
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
24 Aug 2021
24 Aug 2021
Historique:
received:
20
06
2021
revised:
05
08
2021
accepted:
16
08
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
29
9
2021
Statut:
epublish
Résumé
With the aim of describing the burden and epidemiology of community-acquired/healthcare-associated and hospital-acquired bloodstream infections (CA/HCA-BSIs and HA-BSIs) in patients hospitalised with COVID-19, and evaluating the risk factors for BSIs and their relative impact on mortality, an observational cohort study was performed on patients hospitalised with COVID-19 at San Paolo Hospital in Milan, Italy from 24 February to 30 November 2020. Among 1351 consecutive patients hospitalised with COVID-19, 18 (1.3%) had CA/HCA-BSI and 51 (3.8%) HA-BSI for a total of 82 episodes of BSI. The overall incidence of HA-BSI was 3.3/1000 patient-days (95% CI 2.4-4.2). Patients with HA-BSI had a longer hospital stay compared to CA/HCA-BSI and no-BSI groups (27 (IQR 21-35) vs. 12 (7-29) vs. 9 (5-17) median-days,
Identifiants
pubmed: 34572613
pii: antibiotics10091031
doi: 10.3390/antibiotics10091031
pmc: PMC8470708
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Eur J Clin Invest. 2020 Oct;50(10):e13319
pubmed: 32535894
Clin Infect Dis. 2020 Dec 17;71(10):2736-2743
pubmed: 32361747
Rheum Dis Clin North Am. 2016 Feb;42(1):157-76, ix-x
pubmed: 26611557
J Infect. 2021 Feb;82(2):e20-e21
pubmed: 32956729
Int J Environ Res Public Health. 2021 Apr 20;18(8):
pubmed: 33923992
Clin Microbiol Infect. 2021 Jul 7;:
pubmed: 34242804
J Infect Public Health. 2021 May;14(5):555-560
pubmed: 33848884
Clin Microbiol Infect. 2021 Jan;27(1):83-88
pubmed: 32745596
N Engl J Med. 2021 Feb 25;384(8):693-704
pubmed: 32678530
Infect Dis (Lond). 2020 Nov - Dec;52(12):919-922
pubmed: 32779951
Clin Microbiol Infect. 2012 Sep;18(9):E355-61
pubmed: 22784359
J Intensive Care. 2021 Jan 18;9(1):10
pubmed: 33461613
Intensive Care Med. 2021 Feb;47(2):180-187
pubmed: 33506379
J Infect. 2020 Aug;81(2):266-275
pubmed: 32473235
N Engl J Med. 2020 Jun 11;382(24):2372-2374
pubmed: 32302078
Clin Microbiol Infect. 2020 Jul;26(7):808-810
pubmed: 32360446
Clin Microbiol Infect. 2021 Mar;27(3):451-457
pubmed: 33223114
Clin Microbiol Infect. 2020 Dec;26(12):1622-1629
pubmed: 32711058
Mol Cell Endocrinol. 2011 Mar 15;335(1):2-13
pubmed: 20398732
Clin Infect Dis. 2020 Dec 3;71(9):2459-2468
pubmed: 32358954
BMC Infect Dis. 2014 Jan 09;14:13
pubmed: 24405683
JAMA. 2013 Jan 16;309(3):275-82
pubmed: 23321766
Clin Microbiol Infect. 2020 Oct;26(10):1395-1399
pubmed: 32603803
J Glob Antimicrob Resist. 2020 Dec;23:290-291
pubmed: 33130024
Cancer. 2008 Jun;112(11):2384-92
pubmed: 18404699
J Hosp Infect. 2021 Jan;107:95-97
pubmed: 33217490
Euro Surveill. 2012 Nov 15;17(46):
pubmed: 23171822
Influenza Other Respir Viruses. 2016 Sep;10(5):394-403
pubmed: 27232677