Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance.

BRCA1/2 germline mutations male breast cancer molecular subtypes transcriptome profiling

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
08 Sep 2021
Historique:
received: 30 07 2021
revised: 30 08 2021
accepted: 01 09 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 29 9 2021
Statut: epublish

Résumé

Male breast cancer (MBC) is a rare and understudied disease compared with female BC. About 15% of MBCs are associated with germline mutation in BC susceptibility genes, mainly

Identifiants

pubmed: 34572741
pii: cancers13184515
doi: 10.3390/cancers13184515
pmc: PMC8469418
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Associazione Italiana per la Ricerca sul Cancro
ID : IG2018-21389
Organisme : Lega italiana per la lotta contro i tumori (LILT)
ID : IG2019
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : Dipartimenti di Eccellenza-L. 232/2016

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Auteurs

Veronica Zelli (V)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Valentina Silvestri (V)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Virginia Valentini (V)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Agostino Bucalo (A)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Piera Rizzolo (P)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Ines Zanna (I)

Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 08518 Florence, Italy.

Simonetta Bianchi (S)

Division of Pathological Anatomy, Department of Health Sciences, University of Florence, 08518 Florence, Italy.

Anna Coppa (A)

Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Giuseppe Giannini (G)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Laura Cortesi (L)

Department of Oncology and Haematology, University of Modena and Reggio Emilia, 41124 Modena, Italy.

Daniele Calistri (D)

IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.

Maria Grazia Tibiletti (MG)

Department of Pathology, ASST Settelaghi and Centro di Ricerca per lo Studio dei Tumori Eredo-Familiari, Università dell'Insubria, 21100 Varese, Italy.

Stephen B Fox (SB)

Department of Pathology, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC 3000, Australia.

kCon Fab (K)

Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Research Department, PeterMacCallum Cancer Centre, Melbourne, VIC 3000, Australia.

Domenico Palli (D)

Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 08518 Florence, Italy.

Laura Ottini (L)

Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.

Classifications MeSH