Automatic Liver Viability Scoring with Deep Learning and Hyperspectral Imaging.

CNNs artificial intelligence convolutional networks deep learning hepatic artery occlusion hyperspectral imaging liver viability

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
24 Aug 2021
Historique:
received: 18 06 2021
revised: 12 08 2021
accepted: 21 08 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 29 9 2021
Statut: epublish

Résumé

Hyperspectral imaging (HSI) is a non-invasive imaging modality already applied to evaluate hepatic oxygenation and to discriminate different models of hepatic ischemia. Nevertheless, the ability of HSI to detect and predict the reperfusion damage intraoperatively was not yet assessed. Hypoxia caused by hepatic artery occlusion (HAO) in the liver brings about dreadful vascular complications known as ischemia-reperfusion injury (IRI). Here, we show the evaluation of liver viability in an HAO model with an artificial intelligence-based analysis of HSI. We have combined the potential of HSI to extract quantitative optical tissue properties with a deep learning-based model using convolutional neural networks. The artificial intelligence (AI) score of liver viability showed a significant correlation with capillary lactate from the liver surface (r = -0.78,

Identifiants

pubmed: 34573869
pii: diagnostics11091527
doi: 10.3390/diagnostics11091527
pmc: PMC8472457
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Fondation ARC pour la Recherche sur le Cancer
ID : ELIOS
Organisme : Agence Nationale de la Recherche
ID : ANR-18-CE19-0026

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Auteurs

Eric Felli (E)

Hepatology, Department of Biomedical Research, Inselspital, University of Bern, 3008 Bern, Switzerland.
IHU-Strasbourg, Institute of Image-Guided Surgery, 67000 Strasbourg, France.
Institute of Physiology, EA3072 Mitochondria Respiration and Oxidative Stress, University of Strasbourg, 67000 Strasbourg, France.

Mahdi Al-Taher (M)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.

Toby Collins (T)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.

Richard Nkusi (R)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.

Emanuele Felli (E)

Department of General, Digestive, and Endocrine Surgery, University Hospital of Strasbourg, 67000 Strasbourg, France.

Andrea Baiocchini (A)

Department of Pathology, San Camillo Forlanini Hospital, 00152 Rome, Italy.

Veronique Lindner (V)

Department of Pathology, University Hospital of Strasbourg, 67000 Strasbourg, France.

Cindy Vincent (C)

IHU-Strasbourg, Institute of Image-Guided Surgery, 67000 Strasbourg, France.

Manuel Barberio (M)

Department of General Surgery, Cardinale Giovanni Panico Hospital, 73039 Tricase, Italy.

Bernard Geny (B)

Institute of Physiology, EA3072 Mitochondria Respiration and Oxidative Stress, University of Strasbourg, 67000 Strasbourg, France.

Giuseppe Maria Ettorre (GM)

San Camillo Forlanini Hospital, Department of Transplantation and General Surgery, 00152 Rome, Italy.

Alexandre Hostettler (A)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.

Didier Mutter (D)

Department of General, Digestive, and Endocrine Surgery, University Hospital of Strasbourg, 67000 Strasbourg, France.

Sylvain Gioux (S)

Photonics Instrumentation for Health, iCube Laboratory, University of Strasbourg, 67000 Strasbourg, France.

Catherine Schuster (C)

INSERM, Institute of Viral and Liver Disease, U1110, 67000 Strasbourg, France.

Jacques Marescaux (J)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.

Jordi Gracia-Sancho (J)

Hepatology, Department of Biomedical Research, Inselspital, University of Bern, 3008 Bern, Switzerland.
Liver Vascular Biology, IDIBAPS Biomedical Research Institute and CIBEREHD, 08036 Barcelona, Spain.

Michele Diana (M)

Research Institute against Digestive Cancer (IRCAD), 67000 Strasbourg, France.
Liver Vascular Biology, IDIBAPS Biomedical Research Institute and CIBEREHD, 08036 Barcelona, Spain.

Classifications MeSH