Optical Coherence Tomography Angiography in Type 1 Diabetes Mellitus. Report 4: Glycated Haemoglobin.
HbA1c
diabetic retinopathy
foveal avascular zone
glycated haemoglobin
macular thickness
oculomics
optical coherence tomography
optical coherence tomography angiography
perfusion density
vessel density
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
25 Aug 2021
25 Aug 2021
Historique:
received:
30
07
2021
revised:
20
08
2021
accepted:
20
08
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
29
9
2021
Statut:
epublish
Résumé
The purpose of this study was to evaluate specifically the relationship between glycated haemoglobin (HbA1c) levels and retinal optical coherence tomography (OCT) and OCT angiography (OCTA) parameters in type 1 Diabetes Mellitus (DM). A total of 478 type 1 DM patients and 115 controls were included in a prospective OCTA trial (ClinicalTrials.gov NCT03422965). Subgroup analysis was performed for controls, no diabetic retinopathy (DM-no DR) and DR patients (DM-DR), and HbA1c levels. OCT and OCTA measurements were compared with HbA1c levels (current and previous 5 years). DM-no DR patients with HbA1c levels >7.5% showed lower VD than DM-DR and controls (20.16 vs. 20.22 vs. 20.71,
Identifiants
pubmed: 34573883
pii: diagnostics11091537
doi: 10.3390/diagnostics11091537
pmc: PMC8472643
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT03422965']
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Fundació la Marató de TV3
ID : 201633.10
Organisme : Instituto de Salud Carlos III
ID : PI18/00518
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