Interstitial Ectopic Pregnancy: The Role of Mifepristone in the Medical Treatment.

conservative treatment ectopic pregnancy fertility sparing interstitial pregnancy medical therapy methotrexate mifepristone

Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
17 09 2021
Historique:
received: 22 08 2021
accepted: 15 09 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 30 10 2021
Statut: epublish

Résumé

Interstitial pregnancy is defined as the presence of a gestational sac in the most proximal section of the fallopian tube. Management of interstitial pregnancy remains a debated topic. Depending on hemodynamic stability, size of pregnancy, depth of surrounding myometrium, and desires for future fertility, interstitial pregnancy can be managed medically or surgically. We reviewed the literature in December 2020 using keywords "interstitial pregnancy", "medical treatment", "methotrexate", and "mifepristone". Articles published from January 1991 until 2020 were obtained from databases EMBASE, SCOPUS, and PUBMED. We describe the case of a patient with an interstitial pregnancy that was managed with a total medical approach in August 2020 at Burlo Garofolo Hospital. The patient was asymptomatic and hemodynamically stable, with a high level of serum

Identifiants

pubmed: 34574706
pii: ijerph18189781
doi: 10.3390/ijerph18189781
pmc: PMC8472240
pii:
doi:

Substances chimiques

Mifepristone 320T6RNW1F
Methotrexate YL5FZ2Y5U1

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Guglielmo Stabile (G)

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Federico Romano (F)

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Giulia Zinicola (G)

Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Ghergana Alexandrova Topouzova (GA)

Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.

Giovanni Di Lorenzo (G)

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Francesco Paolo Mangino (FP)

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Giuseppe Ricci (G)

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.

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Classifications MeSH