Long-Term Neuropsychological Outcomes Following Temporal Lobe Epilepsy Surgery: An Update of the Literature.

cognitive outcome long-term follow-up memory neurosurgery refractory temporal seizures

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
03 Sep 2021
Historique:
received: 21 07 2021
revised: 27 08 2021
accepted: 30 08 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 29 9 2021
Statut: epublish

Résumé

We present an update of the literature concerning long-term neuropsychological outcomes following surgery for refractory temporal lobe epilepsy (TLE). A thorough search was conducted through the PubMed and Medline electronic databases for studies investigating neuropsychological function in adult patients undergoing resective TLE surgery and followed for a mean/median > five years period. Two independent reviewers screened citations for eligibility and assessed relevant studies for the risk of bias. We found eleven studies fulfilling the above requirements. Cognitive function remained stable through long-term follow up despite immediate post-surgery decline; a negative relation between seizure control and memory impairment has emerged and a possible role of more selective surgery procedures is highlighted.

Identifiants

pubmed: 34574930
pii: healthcare9091156
doi: 10.3390/healthcare9091156
pmc: PMC8466433
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Ioanna Alexandratou (I)

Department of Neurology, Evangelismos Hospital, Ipsilantou 45-47, 10676 Athens, Greece.

Panayiotis Patrikelis (P)

First Department of Neurosurgery, School of Medicine, National and Kapodistrian University of Athens, 10676 Athens, Greece.

Lambros Messinis (L)

Lab of Cognitive Neuroscience, Department of Psychology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Department of Psychiatry, University of Patras Medical School, 26504 Patras, Greece.

Athanasia Alexoudi (A)

First Department of Neurosurgery, School of Medicine, National and Kapodistrian University of Athens, 10676 Athens, Greece.

Anastasia Verentzioti (A)

First Department of Neurosurgery, School of Medicine, National and Kapodistrian University of Athens, 10676 Athens, Greece.

Maria Stefanatou (M)

First Department of Neurosurgery, School of Medicine, National and Kapodistrian University of Athens, 10676 Athens, Greece.

Grigorios Nasios (G)

Department of Speech and Language Therapy, School of Health Sciences, University of Ioannina, 45500 Ioannina, Greece.

Vasileios Panagiotopoulos (V)

Department of Neurosurgery, University of Patras Medical School, 26500 Patras, Greece.

Stylianos Gatzonis (S)

First Department of Neurosurgery, School of Medicine, National and Kapodistrian University of Athens, 10676 Athens, Greece.

Classifications MeSH