Antithrombotic Effect of the Ethanol Extract of

Angelica gigas Nakai acetylsalicylic acid anti-platelet aggregation bleeding in the gut improvement of blood circulation side effect thrombus formation

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
09 Sep 2021
Historique:
received: 13 08 2021
revised: 07 09 2021
accepted: 07 09 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 29 9 2021
Statut: epublish

Résumé

Cardiovascular diseases, such as stroke, are the most common causes of death in developed countries. Ischemic stroke accounts for 85% of the total cases and is caused by abnormal thrombus formation in the vessels, causing deficient blood and oxygen supply to the brain. Prophylactic treatments include the prevention of thrombus formation, of which the most used is acetylsalicylic acid (ASA); however, it is associated with a high incidence of side effects.

Identifiants

pubmed: 34575088
pii: life11090939
doi: 10.3390/life11090939
pmc: PMC8465650
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Rural Development Administration, Republic of Korea
ID : Cooperative Research Program for Agriculture Science & Technology Development (PJ01561701)

Références

Best Pract Res Clin Gastroenterol. 2001 Oct;15(5):801-20
pubmed: 11566042
J Vis Exp. 2013 May 29;(75):e2609
pubmed: 23748408
Nat Med. 2011 Nov 07;17(11):1391-401
pubmed: 22064429
Curr Med Chem Cardiovasc Hematol Agents. 2004 Apr;2(2):149-56
pubmed: 15320797
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;259(2):211
pubmed: 4232694
Front Biosci (Elite Ed). 2012 Jan 01;4:809-17
pubmed: 22201915
World J Gastroenterol. 2012 May 14;18(18):2147-60
pubmed: 22611307
Lancet. 2015 Jul 18;386(9990):281-91
pubmed: 25777662
Stroke. 2016 Apr;47(4):1165-72
pubmed: 26786115
Arch Pharm Res. 2003 Sep;26(9):723-6
pubmed: 14560920
Curr Opin Hematol. 2006 Jan;13(1):34-9
pubmed: 16319685
J Pharmacol Exp Ther. 1983 Apr;225(1):57-60
pubmed: 6834277
Carcinogenesis. 2009 Mar;30(3):377-86
pubmed: 19136477
J Clin Invest. 2012 Jul;122(7):2331-6
pubmed: 22751108
Rev Bras Reumatol. 2012 Oct;52(5):767-82
pubmed: 23090376
Nat Med. 2002 Nov;8(11):1227-34
pubmed: 12411949
Am J Cardiovasc Drugs. 2005;5(6):399-408
pubmed: 16259528
Experientia. 1969 Nov 15;25(11):1224
pubmed: 5357845
Gastroenterology. 2004 Jul;127(1):94-104
pubmed: 15236176
Nat Med. 2011 Jul 07;17(7):796-808
pubmed: 21738161
Br J Clin Pharmacol. 1991 Jul;32(1):77-83
pubmed: 1888645
Gastroenterology. 1989 Feb;96(2 Pt 2 Suppl):606-14
pubmed: 2491826
Curr Med Chem. 2013;20(22):2779-97
pubmed: 23590713
N Engl J Med. 1999 Jun 17;340(24):1888-99
pubmed: 10369853
Clin Cancer Res. 2015 Apr 1;21(7):1543-8
pubmed: 25501125
Stroke. 1990 Dec;21(12 Suppl):IV12-23
pubmed: 2124385
Circulation. 2011 Mar 1;123(8):933-44
pubmed: 21262990
Neurotherapeutics. 2016 Oct;13(4):661-670
pubmed: 27730544
J Thromb Haemost. 2011 Jul;9 Suppl 1:92-104
pubmed: 21781245
Front Pharmacol. 2017 Aug 22;8:560
pubmed: 28878675
Arch Toxicol. 1978 Oct 13;41(1):99-105
pubmed: 718423
World J Gastroenterol. 2004 Jul 1;10(13):1854-6
pubmed: 15222022
Hematology Am Soc Hematol Educ Program. 2009;:267-72
pubmed: 20008209
J Pharm Pharmacol. 1968 Apr;20(4):302-4
pubmed: 4384609
Neurobiol Learn Mem. 2003 Jan;79(1):11-8
pubmed: 12482674
Blood. 2002 May 1;99(9):3228-34
pubmed: 11964287
Redox Biol. 2018 Apr;14:126-130
pubmed: 28888895
J Microbiol Biotechnol. 2009 Dec;19(12):1569-72
pubmed: 20075620
Gastroenterology. 1993 Sep;105(3):715-24
pubmed: 8103026
BMC Complement Altern Med. 2015 Apr 01;15:101
pubmed: 25888524
Nat New Biol. 1971 Jun 23;231(25):232-5
pubmed: 5284360
Oncol Lett. 2018 Jun;15(6):8454-8460
pubmed: 29805582
Biomol Ther (Seoul). 2016 Nov 1;24(6):659-664
pubmed: 27302963

Auteurs

Pia Loreto Werlinger Bravo (PLW)

Graduate School of Interdisciplinary Program of Biomodulation, Myongji University, Yongin 17058, Korea.

Hui Jin (H)

Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Korea.

Hyunwoo Park (H)

Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Korea.
Health Park Co., Ltd., Seoul 06627, Korea.

Min Sang Kim (MS)

Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Korea.

Hirofumi Matsui (H)

Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.

Hanki Lee (H)

Graduate School of Interdisciplinary Program of Biomodulation, Myongji University, Yongin 17058, Korea.
Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Korea.

Joo-Won Suh (JW)

Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Korea.
MJ Bioefficacy Research Center, Myongji University, Yongin 17058, Korea.

Classifications MeSH