Assessing mPTC Progression during Active Surveillance: Volume or Diameter Increase?
active surveillance
differentiated thyroid cancer
management
observation
papillary thyroid microcarcinoma
tailored treatment for thyroid cancer
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
09 Sep 2021
09 Sep 2021
Historique:
received:
01
07
2021
revised:
02
09
2021
accepted:
05
09
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
29
9
2021
Statut:
epublish
Résumé
Active surveillance (AS) is considered an alternative to immediate surgery in micropapillary thyroid carcinoma (mPTC). However, the definition of clinical mPTC progression during AS is controversial. We evaluated changes in tumor size using both tumor diameters and volume in 109 patients with mPTC followed in an AS protocol for a mean period of 31 ± 18 months. At the time of data lock, 19/109 (17.4%) mPTC reached and maintained a volume increase of ≥50%. However, only 3/19 (15.7%) showed progression, according to the diameter increase. The remaining 16 showed a slight diameter growth without reaching the original protocol progression criteria. The mean mPTC growth rate in stable cases was 0.37 mm
Identifiants
pubmed: 34575179
pii: jcm10184068
doi: 10.3390/jcm10184068
pmc: PMC8471696
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : 2017YTWKWH
Organisme : Associazione Italiana per la Ricerca sul Cancro
ID : one-year fellowship Angela Roi
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