Xanthone Glucosides: Isolation, Bioactivity and Synthesis.

9H-xanthen-9-one chemical synthesis pharmacological activity xanthone C-glucoside xanthone O-glucoside

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
14 Sep 2021
Historique:
received: 17 08 2021
revised: 06 09 2021
accepted: 09 09 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 12 11 2021
Statut: epublish

Résumé

Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria from a variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, anti-malarial, anti-tuberculosis, and cytotoxic properties. Xanthone glucosides are a significant branch of xanthones. After glycosylation, xanthones may have improved characteristics (such as solubility and pharmacological activity). Currently, no critical review of xanthone glucosides has been published. A literature survey including reports of naturally occurring xanthone glucosides is included in this review. The isolation, structure, bioactivity, and synthesis of these compounds were all explored in depth.

Identifiants

pubmed: 34577044
pii: molecules26185575
doi: 10.3390/molecules26185575
pmc: PMC8465223
pii:
doi:

Substances chimiques

Glucosides 0
Xanthones 0
xanthone 9749WEV0CA

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Natural Science Foundation of China
ID : 81973438
Organisme : the NSFC-Joint Foundation of Yunnan Province
ID : U1902213
Organisme : Fok Ying Tong Education Foundation
ID : 161039
Organisme : the Guangdong Province Key Area R&D Program of China
ID : 2020B1111110003
Organisme : The Three-year development plan project for Traditional Chinese Medicine
ID : ZY(2018-2020)-CCCX-2001-02

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Auteurs

Qing Huang (Q)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

Youyi Wang (Y)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

Huaimo Wu (H)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

Man Yuan (M)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

Changwu Zheng (C)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

Hongxi Xu (H)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.

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