PRODH/POX-Dependent Celecoxib-Induced Apoptosis in MCF-7 Breast Cancer.
PRODH/POX
apoptosis
breast cancer
proline
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
29 Aug 2021
29 Aug 2021
Historique:
received:
23
07
2021
revised:
24
08
2021
accepted:
26
08
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
29
9
2021
Statut:
epublish
Résumé
Celecoxib (Cx), an inhibitor of cyclooxygenase 2, induces apoptosis of cancer cells. However, the mechanism of the chemopreventive effect remains not fully understood. We aimed to investigate the role of PRODH/POX that is involved in the regulation of apoptosis induced by celecoxib. MCF-7 breast cancer cell line and the corresponding MCF-7 cell line with silenced PRODH/POX (MCF-7
Identifiants
pubmed: 34577574
pii: ph14090874
doi: 10.3390/ph14090874
pmc: PMC8471327
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Uniwersytet Medyczny w Bialymstoku
ID : N/ST/ZB/18/001/2227
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