Treatments for HBV: A Glimpse into the Future.

Animals Antiviral Agents / pharmacology Genetic Therapy Hepatitis B / therapy Hepatitis B Vaccines Hepatitis B virus Hepatitis B, Chronic / therapy Hepatocytes / virology Humans Immunotherapy Life Cycle Stages
HBV direct antiviral agents gene therapy immunotherapy therapeutic vaccines

Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
04 09 2021
Historique:
received: 19 05 2021
revised: 17 08 2021
accepted: 24 08 2021
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 15 2 2022
Statut: epublish

Résumé

The hepatitis B virus is responsible for most of the chronic liver disease and liver cancer worldwide. As actual therapeutic strategies have had little success in eradicating the virus from hepatocytes, and as lifelong treatment is often required, new drugs targeting the various phases of the hepatitis B virus (HBV) lifecycle are currently under investigation. In this review, we provide an overview of potential future treatments for HBV.

Identifiants

DOI: 10.3390/v13091767 PMID: 34578347 PMC: PMC8473442
pubmed: 34578347
pii: v13091767
doi: 10.3390/v13091767
pmc: PMC8473442
pii:
doi:

Substances chimiques

Antiviral Agents 0
Hepatitis B Vaccines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Alessandra Bartoli (A)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.
Postgraduate School of Allergy and Clinical Immunology, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Filippo Gabrielli (F)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.
Postgraduate School of Internal Medicine, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Andrea Tassi (A)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.
Postgraduate School of Internal Medicine, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Carmela Cursaro (C)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Ambra Pinelli (A)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.
Postgraduate School of Allergy and Clinical Immunology, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Pietro Andreone (P)

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.
Postgraduate School of Allergy and Clinical Immunology, University of Modena and Reggio Emilia, 41126 Modena, Italy.
ORCID: 0000-0002-4794-9809

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Thérapie génétique › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Hépatite › Hépatites virales humaines › Hépatite B › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antiviraux › Vaccins contre les hépatites virales › Vaccins anti-hépatite B › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Virus › Virus de l'hépatite › Hepadnaviridae › Orthohepadnavirus › Virus de l'hépatite B › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Hépatite chronique › Hépatite B chronique › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Thérapeutique › Biothérapie › Immunothérapie › Treatments for HBV: A Glimpse into the Future.
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Métamorphose biologique › Étapes du cycle de vie › Treatments for HBV: A Glimpse into the Future.