Acute macular neuroretinopathy (AMN) following COVID-19 vaccination.

AMN COVID-19 vaccine vaxzevria EZ disruption IZ disruption Paracentral scotomas

Journal

American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 22 04 2021
revised: 14 07 2021
accepted: 20 09 2021
pubmed: 29 9 2021
medline: 29 9 2021
entrez: 28 9 2021
Statut: ppublish

Résumé

To describe a case of acute macular neuroretinopathy (AMN) in a 23-year-old Caucasian female after a COVID-19 vaccination (Vaxzevira). Our patient perceived visual symptoms in both eyes one day after COVID-19 vaccination. Hyporeflective petalloid shaped perifoveal lesions appeared in infrared reflectance (IR) imaging, and Spectral domain-optical coherence tomography (SD-OCT) revealed structural alterations of outer retinal layers that resulted in persistent disruption of the ellipsoid zone (EZ) and the interdigitation zone (IZ). We report a novel association between AMN and COVID-19 vaccination. In addition to a febrile infection and oral contraception, previous vaccination should also be considered a potential risk factor for AMN.

Identifiants

pubmed: 34580648
doi: 10.1016/j.ajoc.2021.101207
pii: S2451-9936(21)00216-4
pmc: PMC8457905
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101207

Informations de copyright

© 2021 The Authors.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest.

Auteurs

Daniela Drüke (D)

University Medical Center Goettingen, Department of Ophthalmology, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Uwe Pleyer (U)

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Department of Ophthalmology, Campus Virchow, Charité, 13353, Berlin, Germany.

Hans Hoerauf (H)

University Medical Center Goettingen, Department of Ophthalmology, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Nicolas Feltgen (N)

University Medical Center Goettingen, Department of Ophthalmology, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Sebastian Bemme (S)

University Medical Center Goettingen, Department of Ophthalmology, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Classifications MeSH