[Chemical constituents of triterpenoids from Euphorbia resinifera].

Euphorbia resinifera structure identification triterpenoid

Journal

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
ISSN: 1001-5302
Titre abrégé: Zhongguo Zhong Yao Za Zhi
Pays: China
ID NLM: 8913656

Informations de publication

Date de publication:
Sep 2021
Historique:
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 30 9 2021
Statut: ppublish

Résumé

The combination of normal-phase silica gel column chromatography, octadecyl silica(ODS) column chromatography, semi-preparative high performance liquid chromatography(HPLC), etc. was employed to isolate and purify the chemical components from Euphorbia resinifera, and 7 triterpenoids were separated from the ethanol extract of the medicinal materials. Their structures were identified by various spectroscopy methods as cycloartan-1,24-diene-3-one(1), cycloartan-1,24-diene-3-ol(2), 3β-hydroxy-lanosta-8,24-diene-11-one(3), lnonotusane C(4), eupha-8,24-diene-3β-ol-7,11-dione(5), eupha-24-methylene-8-ene-3β-ol-7,11-dione(6), and eupha-8,24-diene-3β,11β-diol-7-one(7). Compounds 1 and 2 are new compounds, and compound 3 is obtained from nature for the first time.

Identifiants

pubmed: 34581047
doi: 10.19540/j.cnki.cjcmm.20210621.201
doi:

Substances chimiques

Drugs, Chinese Herbal 0
Triterpenes 0

Types de publication

Journal Article

Langues

chi

Sous-ensembles de citation

IM

Pagination

4433-4437

Auteurs

Ya-Jie Li (YJ)

College of Pharmacy, Xinjiang Medical University Urumqi 830011, China.

Teng-Fei Ji (TF)

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences &Peking Union Medical College Beijing 100050, China.

Jun Zhao (J)

Xinjiang Key Laboratory for Uighur Medicines,Xinjiang Institute of Materia Medica Urumqi 830004, China.

Zheng-Yi Gu (ZY)

Xinjiang Key Laboratory for Uighur Medicines,Xinjiang Institute of Materia Medica Urumqi 830004, China.

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Classifications MeSH