Endobronchial mucoepidermoid carcinoma in a child with postinfectious bronchiolitis obliterans.


Journal

Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590

Informations de publication

Date de publication:
12 2021
Historique:
revised: 27 08 2021
received: 26 03 2021
accepted: 30 08 2021
pubmed: 29 9 2021
medline: 25 12 2021
entrez: 28 9 2021
Statut: ppublish

Résumé

Endobronchial mucoepidermoid tumors are rare neoplasms. Due to nonspecific symptoms, diagnosis can be challenging, but early diagnosis and treatment are crucial for prognosis. We present the case of a boy, with chronic respiratory insufficiency due to bronchiolitis obliterans, that presented worsening exertional dyspnea at 12 years. Spirometry showed unexpected deterioration of respiratory function and a computed tomography scan revealed an obstructive polypoid mass in the intermediate bronchus. Given the severe basal ventilatory compromise and risk associated with surgical treatment, rigid bronchoscopy, and laser photocoagulation were performed, with clinical and functional improvement. The histological examination revealed a low-grade mucoepidermoid carcinoma. The option for a minimally invasive procedure requires careful follow-up due to the risk of tumor recurrence.

Identifiants

pubmed: 34583420
doi: 10.1002/ppul.25685
doi:

Types de publication

Case Reports Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

4063-4065

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

Eyssartier E, Ang P, Bonnemaison E, et al. Characteristics of endobronchial primitive tumors in children. Pediatr Pulmonol. 2014;49:E121-E125.
Yang HM, Yin J, Li G, Liu XC. Clinical features and interventional bronchoscopic treatment of primary airway tumor in 8 children. Zhonghua Er Ke Za Zhi. 2021;59(1):27-32.
Wang H, Zhang N, Tao M, et al. Application of interventional bronchoscopic therapy in eight pediatric patients with malignant airway tumors. Tumori. 2012;98:581-587.
Wang H, Zhang J, Li D, Zhang N, Li J, Mao J. Efficacy of bronchoscopic therapies for bronchial mucoepidermoid carcinoma in children: results from six patients. Tumori. 2015;101(1):52-56.
Bolliger CT, Sutedja TG, Strausz J, Freitag L. Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J. 2006;27:1258-1271.

Auteurs

Sara Fonseca (S)

Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.

Sónia Silva (S)

Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.

Adriana Magalhães (A)

Pneumology Department, Centro Hospitalar Universitário São João, Porto, Portugal.

Rita Lago (R)

Radiotherapy Department, Centro Hospitalar Universitário São João, Porto, Portugal.

Norberto Estevinho (N)

Pediatric Surgery Department, Centro Hospitalar Universitário de São João, Porto, Portugal.

Maria do Bom-Sucesso (MD)

Pediatric Oncology Department, Centro Hospitalar Universitário de São João, Porto, Portugal.
Gynecology, Obstetrics and Pediatrics Department, Faculty of Medicine of the University of Porto, Porto, Portugal.

Inês Azevedo (I)

Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.
Gynecology, Obstetrics and Pediatrics Department, Faculty of Medicine of the University of Porto, Porto, Portugal.
EpiUnit, Public Health Institute, University of Porto, Porto, Portugal.

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