Development of 1,3-diynyl derivatives of noscapine as potent tubulin binding anticancer agents for the management of breast cancer.

Humans Female Noscapine Breast Neoplasms / drug therapy Tubulin / metabolism Antineoplastic Agents / pharmacology Cell Proliferation Diynes / pharmacology Cell Line, Tumor
1 3-diynyl-noscapinoids Noscapine anticancer agents breast cancer tubulin binding

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
2022
Historique:
pubmed: 30 9 2021
medline: 28 12 2022
entrez: 29 9 2021
Statut: ppublish

Résumé

We developed 1,3-diynyl derivatives of noscapine (an opium alkaloid) through

Identifiants

DOI: 10.1080/07391102.2021.1982008 PMID: 34583618
pubmed: 34583618
doi: 10.1080/07391102.2021.1982008
doi:

Substances chimiques

Noscapine 8V32U4AOQU
Tubulin 0
Antineoplastic Agents 0
Diynes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13136-13153

Auteurs

Rajesh Kumar Meher (RK)

Centre of Excellence in Natural C and Therapeutics, Department of Biotechnology and Bioinformatics, Sambalpur University, Sambalpur, Odisha, India.

Pratyush Pragyandipta (P)

Centre of Excellence in Natural C and Therapeutics, Department of Biotechnology and Bioinformatics, Sambalpur University, Sambalpur, Odisha, India.

Praveen Kumar Reddy (PK)

Fluoro and Agrochemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, India.

Ravikumar Pedaparti (R)

Fluoro and Agrochemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, India.

Srinivas Kantevari (S)

Fluoro and Agrochemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, India.
ORCID: 0000-0003-4270-9651

Pradeep K Naik (PK)

Centre of Excellence in Natural C and Therapeutics, Department of Biotechnology and Bioinformatics, Sambalpur University, Sambalpur, Odisha, India.
ORCID: 0000-0001-7044-2427

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoquinoléines › Noscapine › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Tubuline › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures acycliques › Alcynes › Polyynes › Diynes › Development of 1,3-diynyl derivatives of...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Development of 1,3-diynyl derivatives of...