Ononin alleviates H
5' AMP-activated protein kinase/mTOR
apoptosis
autophagy
cardiac function
cardiomyocyte
ononin
Journal
Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
20
02
2021
accepted:
07
06
2021
entrez:
29
9
2021
pubmed:
30
9
2021
medline:
30
9
2021
Statut:
ppublish
Résumé
Ononin (ON) is an isoflavone with numerous reported bioactivities, including anti-oxidative, anti-inflammatory and neuroprotective effects. Autophagy is a critical homeostatic process in the body that has been reported to closely associate with the apoptotic processes of cardiomyocytes. Using flow cytometry, western blotting, echocardiography and Masson's staining, the present study investigated the effects of ON on H
Identifiants
pubmed: 34584565
doi: 10.3892/etm.2021.10742
pii: ETM-0-0-10742
pmc: PMC8461629
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1307Informations de copyright
Copyright: © Pan et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Stem Cell Res Ther. 2017 Nov 2;8(1):242
pubmed: 29096705
Int J Cell Biol. 2014;2014:502676
pubmed: 24639873
Exp Biol Med (Maywood). 2009 Oct;234(10):1212-9
pubmed: 19596825
Autophagy. 2015;11(12):2375-6
pubmed: 26565689
Cell Cycle. 2015;14(11):1631-42
pubmed: 25927598
J Mol Cell Cardiol. 2014 Jun;71:54-61
pubmed: 24239608
Adv Exp Med Biol. 2019;1206:67-83
pubmed: 31776980
Biomed Pharmacother. 2018 Aug;104:485-495
pubmed: 29800913
Oxid Med Cell Longev. 2019 Jul 1;2019:3206542
pubmed: 31354905
J Agric Food Chem. 2018 Mar 21;66(11):2917-2924
pubmed: 29504397
Int J Mol Sci. 2017 Sep 22;18(10):
pubmed: 28937652
Int J Cardiol. 2016 Jan 1;202:433-40
pubmed: 26433167
Cell. 2008 Jan 11;132(1):27-42
pubmed: 18191218
Cardiovasc Hematol Agents Med Chem. 2014;12(2):60-5
pubmed: 25613032
Future Med Chem. 2016;8(3):245-8
pubmed: 26900018
Biomed Pharmacother. 2018 Jan;97:594-599
pubmed: 29101802
Acta Physiol (Oxf). 2018 Aug;223(4):e13074
pubmed: 29660243
Mol Cell. 2020 Mar 5;77(5):951-969.e9
pubmed: 31995728
Autophagy. 2009 Feb;5(2):184-93
pubmed: 19098447
Nutrients. 2019 Dec 02;11(12):
pubmed: 31810345
Physiol Rev. 2019 Oct 1;99(4):1765-1817
pubmed: 31364924
Biomolecules. 2018 Mar 21;8(2):
pubmed: 29561758
Mol Immunol. 2017 Mar;83:46-51
pubmed: 28095349
Front Physiol. 2020 Dec 17;11:619730
pubmed: 33391038
Front Pharmacol. 2019 Oct 31;10:1295
pubmed: 31749703
Ann Transl Med. 2019 Jul;7(14):326
pubmed: 31475196
Metabolomics. 2019 Nov 25;15(12):153
pubmed: 31768751
J Pathol. 2010 May;221(1):3-12
pubmed: 20225336
Ann N Y Acad Sci. 2020 May;1467(1):3-20
pubmed: 31985829
J Biomed Sci. 2015 Mar 18;22:18
pubmed: 25879197
Circ Res. 2018 Apr 13;122(8):1151-1163
pubmed: 29650632
Int J Legal Med. 2018 Mar;132(2):425-438
pubmed: 29362873
Phytomedicine. 2009 Apr;16(4):314-9
pubmed: 18757188
J Nutr. 2010 Jul;140(7):1350S-4S
pubmed: 20484551
Cell Biol Int. 2019 Jun;43(6):582-592
pubmed: 30958602
Front Pharmacol. 2019 May 31;10:551
pubmed: 31214022
Circ Res. 2018 Feb 2;122(3):489-505
pubmed: 29420210
Cell Death Differ. 2018 Mar;25(3):486-541
pubmed: 29362479