Amyotrophic lateral sclerosis in a patient who recovered from Miller Fisher Syndrome: The role of GQ1b antibody revisited.
Amyotrophic lateral sclerosis
GQ1b
Ganglioside antibodies
Miller Fisher syndrome
Journal
Brain, behavior, & immunity - health
ISSN: 2666-3546
Titre abrégé: Brain Behav Immun Health
Pays: United States
ID NLM: 101759062
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
20
10
2020
revised:
23
02
2021
accepted:
24
02
2021
entrez:
30
9
2021
pubmed:
1
10
2021
medline:
1
10
2021
Statut:
epublish
Résumé
Miller Fisher Syndrome (MFS), a variant of Guillain Barre Syndrome (GBS), and amyotrophic lateral sclerosis (ALS) are two rare neuromuscular diseases that are usually unrelated. While ganglioside antibodies have a common relation with MFS and GBS, they have also been found in association, albeit less commonly, with ALS. A patient experiencing MFS and then ALS in tandem has never been documented. We discuss a case demonstrating these findings, with GQ1b elevated on both occasions. The pathophysiologic role of GQ1b is explored.
Identifiants
pubmed: 34589746
doi: 10.1016/j.bbih.2021.100231
pii: S2666-3546(21)00034-X
pmc: PMC8474546
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100231Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors have no financial or other conflicting interests to declare.
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