Correlating ROS1 Protein Expression With

Amplifications Fusions Mutations Protein expression ROS1

Journal

JTO clinical and research reports
ISSN: 2666-3643
Titre abrégé: JTO Clin Res Rep
Pays: United States
ID NLM: 101769967

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 11 09 2020
accepted: 11 09 2020
entrez: 30 9 2021
pubmed: 1 10 2021
medline: 1 10 2021
Statut: epublish

Résumé

In this study, we sought to further characterize ROS1 protein expression in solid tumors with the complete spectrum of ROS1 immunohistochemistry (IHC) was performed using the ROS1 (SP384) class I assay per manufacturer's instructions on a variety of solid tumors (n = 32) with known Of the 32 cases with ROS1 IHC results, 100% (11 of 11) with canonical These findings suggest that if ROS1 IHC was used as a screening tool for

Identifiants

pubmed: 34589979
doi: 10.1016/j.jtocrr.2020.100100
pii: S2666-3643(20)30146-6
pmc: PMC8474213
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100100

Informations de copyright

© 2020 The Authors.

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Auteurs

Richard S P Huang (RSP)

Foundation Medicine, Inc., Morrisville, North Carolina.

Amanda Gottberg-Williams (A)

Foundation Medicine, Inc., Morrisville, North Carolina.

Panhia Vang (P)

Foundation Medicine, Inc., Morrisville, North Carolina.

Shoua Yang (S)

Foundation Medicine, Inc., Morrisville, North Carolina.

Nicholas Britt (N)

Foundation Medicine, Inc., Morrisville, North Carolina.

Jaspreet Kaur (J)

Foundation Medicine, Inc., Cambridge, Massachusetts.

James Haberberger (J)

Foundation Medicine, Inc., Morrisville, North Carolina.

Natalie Danziger (N)

Foundation Medicine, Inc., Cambridge, Massachusetts.

Clarence Owens (C)

Foundation Medicine, Inc., Morrisville, North Carolina.

Sara E Beckloff (SE)

Foundation Medicine, Inc., Morrisville, North Carolina.

Jeffrey S Ross (JS)

Foundation Medicine, Inc., Cambridge, Massachusetts.
Department of Pathology, State University of New York (SUNY) Upstate Medical University, Syracuse, New York.

Shakti H Ramkissoon (SH)

Foundation Medicine, Inc., Morrisville, North Carolina.
Department of Pathology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Classifications MeSH