Erythropoietin Produces a Dual Effect on Carotid Body Chemoreception in Male Rats.

chemosensing electrophysiology hypercapnia hypoxia nitric oxide

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2021
Historique:
received: 18 06 2021
accepted: 25 08 2021
entrez: 1 10 2021
pubmed: 2 10 2021
medline: 2 10 2021
Statut: epublish

Résumé

Erythropoietin (EPO) regulates respiration under conditions of normoxia and hypoxia through interaction with the respiratory centers of the brainstem. Here we investigate the dose-dependent impact of EPO in the CB response to hypoxia and hypercapnia. We show, in isolated "

Identifiants

pubmed: 34594222
doi: 10.3389/fphar.2021.727326
pii: 727326
pmc: PMC8476757
doi:

Types de publication

Journal Article

Langues

eng

Pagination

727326

Informations de copyright

Copyright © 2021 Arias-Reyes, Laouafa, Zubieta-DeUrioste, Joseph, Bairam, Schneider Gasser and Soliz.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Christian Arias-Reyes (C)

Université Laval, Faculté de Médecine, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Pédiatrie, Québec, QC, Canada.

Sofien Laouafa (S)

Université Laval, Faculté de Médecine, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Pédiatrie, Québec, QC, Canada.

Natalia Zubieta-DeUrioste (N)

High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA), La Paz, Bolivia.

Vincent Joseph (V)

Université Laval, Faculté de Médecine, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Pédiatrie, Québec, QC, Canada.

Aida Bairam (A)

Université Laval, Faculté de Médecine, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Pédiatrie, Québec, QC, Canada.

Edith M Schneider Gasser (EM)

Institute of Veterinary Physiology, Vetsuisse-Faculty, University of Zurich, Zurich, Switzerland.
Center for Neuroscience Zurich (ZNZ), Zurich, Switzerland.

Jorge Soliz (J)

Université Laval, Faculté de Médecine, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Département de Pédiatrie, Québec, QC, Canada.
High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA), La Paz, Bolivia.

Classifications MeSH