A Case of Endometrial Carcinosarcoma Containing Sertoliform Endometrioid Carcinoma Component.
Journal
Case reports in pathology
ISSN: 2090-6781
Titre abrégé: Case Rep Pathol
Pays: United States
ID NLM: 101576609
Informations de publication
Date de publication:
2021
2021
Historique:
received:
16
04
2021
revised:
10
08
2021
accepted:
23
08
2021
entrez:
1
10
2021
pubmed:
2
10
2021
medline:
2
10
2021
Statut:
epublish
Résumé
Carcinosarcomas (CSs) of the endometrium have admixture of malignant epithelial and mesenchymal components. The carcinomatous component exhibit endometrioid, serous, or clear cell differentiation, or are undifferentiated. CSs are considered homologous or heterologous according to the type of sarcomatous component. Sertoliform endometrioid carcinomas (SECs) of the endometrium which comprise a rare subtype of endometrial cancer, typically occur in the ovary. SECs as a carcinomatous component of CS of the endometrium have not been reported. Here, we report an endometrial carcinosarcoma that contains an SEC component. An 88-year-old female presented to a clinic with atypical genital bleeding. She was referred to our hospital and underwent total hysterectomy, bilateral adnexectomy and partial omentectomy due to endometrial carcinoma. Gross examination revealed a polypoid mass in the uterine cavity with massive myometrial invasion. Histologically, the tumor was a high-grade endometrioid carcinoma. In addition to an ordinary conventional endometrioid carcinoma, approximately 30% of the area exhibited sex cord-like pattern and contained small hollow tubules, anastomosing cords and trabeculae, and tightly packed nests. Immunohistochemically, the SEC component showed diffuse p53 staining. Sex cord-like area, especially the solid area, showed positive staining for EMA, vimentin,
Identifiants
pubmed: 34594585
doi: 10.1155/2021/5868818
pmc: PMC8478548
doi:
Types de publication
Case Reports
Langues
eng
Pagination
5868818Informations de copyright
Copyright © 2021 Satoru Munakata et al.
Déclaration de conflit d'intérêts
All authors have no conflict of interest.
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