Three Methods for the Solution Phase Synthesis of Cyclic Peptides.
Cyclodepsipeptides
Cyclopeptides
Macrocyclization of peptides
Macrolactamization
Peptide coupling
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
1
10
2021
pubmed:
2
10
2021
medline:
13
1
2022
Statut:
ppublish
Résumé
Cyclic peptides, which often exhibit interesting biological properties, can be obtained by macrolactamization of adequately protected linear peptide chains. Because of the remarkable biological properties, methods for the efficient cyclization of peptides are of high interest. We herein describe three different protocols for the cyclization of peptides and depsipeptides via amide bond formation. These methods can, in principal, be applied to any linear peptide chain.
Identifiants
pubmed: 34596843
doi: 10.1007/978-1-0716-1689-5_4
doi:
Substances chimiques
Peptides, Cyclic
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
43-61Informations de copyright
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.
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