Hyperendemicity of cysticercosis in Madagascar: Novel insights from school children population-based antigen prevalence study.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2021
2021
Historique:
received:
28
08
2020
accepted:
16
09
2021
entrez:
1
10
2021
pubmed:
2
10
2021
medline:
30
11
2021
Statut:
epublish
Résumé
Taenia solium (Ts) cysticercosis is a neglected zoonotic disease particularly prevalent in Madagascar. Few data are available for children, current data mainly rely on antibody prevalence. We sought to determine the Ts-antigen seroprevalence-determining active cysticercosis-amongst school children from various cities in Madagascar (excluding the capital) and evaluated associated risk factors. In seven cities in Madagascar, the presence of cysticercosis in school children (n = 1751) was investigated in 2007 using the B158/B60 antigen (Ag)-ELISA. The overall prevalence based on Ag detection was 27.7% [95%CI: 10-37%]. Risk factors associated with Ag positivity were age, biotope, altitude and annual average rainfall. These results highlight the high prevalence of active cysticercosis in Madagascar among school children in an urban setting. This high prevalence as well as the risk factors unraveled point to the emergency to implement appropriate Public Health measure son a national scale.
Identifiants
pubmed: 34597322
doi: 10.1371/journal.pone.0258035
pii: PONE-D-20-27048
pmc: PMC8486106
doi:
Substances chimiques
Antibodies, Helminth
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0258035Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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