Ketogenic diets in the management of type 1 diabetes: Safe or safety concern?

Diabetes Mellitus, Type 1 / drug therapy Diet, Ketogenic Humans Insulin Ketosis Weight Loss

Journal

Cleveland Clinic journal of medicine
ISSN: 1939-2869
Titre abrégé: Cleve Clin J Med
Pays: United States
ID NLM: 8703441

Informations de publication

Date de publication:
01 Oct 2021
Historique:
entrez: 2 10 2021
pubmed: 3 10 2021
medline: 27 1 2022
Statut: epublish

Résumé

The jury is still out on whether a low-carbohydrate, ketosis-inducing diet is an effective and safe adjunctive therapy to insulin in type 1 diabetes. The limited published literature reports an association with weight loss and improved glycemic control and may, over the long-term, lead to reduced macrovascular and microvascular harm. However, the attendant increased risk of dyslipidemia, diabetic ketoacidosis, and hypoglycemia warrant caution, close monitoring of patients who embark on the diet, and further research.

Identifiants

DOI: 10.3949/ccjm.88a.20121 PMID: 34598919
pubmed: 34598919
pii: 88/10/547
doi: 10.3949/ccjm.88a.20121
doi:

Substances chimiques

Insulin 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

547-555

Informations de copyright

Copyright © 2021 The Cleveland Clinic Foundation. All Rights Reserved.

Auteurs

Lauren Anne Buehler (LA)

Endocrinologist, Conway Medical Center, Conway, SC.

Dawn Noe (D)

Registered Dietitian Nutritionist, Dawn Noe Nutrition and Consulting, Cleveland, OH.

Shannon Knapp (S)

Manager of Diabetes Care and Education, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH.

Diana Isaacs (D)

Pharmacy Clinical Specialist, Continuous Glucose Monitor and Remote Monitoring Program Coordinator, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH.

Kevin M Pantalone (KM)

Staff Endocrinologist, Director of Diabetes Initiatives, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH pentalk@gmail.com.

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Classifications MeSH

questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Diabète de type 1 › Ketogenic diets in the management of type 1...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Régime pauvre en glucides › Régime cétogène › Ketogenic diets in the management of type 1...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Ketogenic diets in the management of type 1...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Ketogenic diets in the management of type 1...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'équilibre acidobasique › Acidose › Cétose › Ketogenic diets in the management of type 1...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Mensurations corporelles › Poids › Modifications du poids corporel › Perte de poids › Ketogenic diets in the management of type 1...