Airborne concentrations of SARS-CoV-2 in indoor community environments in Italy.
Airborne transmission
COVID-19
Coronavirus
Indoor
PCR
SARS-CoV-2
Journal
Environmental science and pollution research international
ISSN: 1614-7499
Titre abrégé: Environ Sci Pollut Res Int
Pays: Germany
ID NLM: 9441769
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
29
07
2021
accepted:
22
09
2021
pubmed:
3
10
2021
medline:
5
2
2022
entrez:
2
10
2021
Statut:
ppublish
Résumé
COVID-19 pandemic raised a debate regarding the role of airborne transmission. Information regarding virus-laden aerosol concentrations is still scarce in community indoors and what are the risks for general public and the efficiency of restriction policies. This work investigates, for the first time in Italy, the presence of SARS-CoV-2 RNA in air samples collected in different community indoors (one train station, two food markets, one canteen, one shopping centre, one hair salon, and one pharmacy) in three Italian cities: metropolitan city of Venice (NE of Italy), Bologna (central Italy), and Lecce (SE of Italy). Air samples were collected during the maximum spread of the second wave of pandemic in Italy (November and December 2020). All collected samples tested negative for the presence of SARS-CoV-2, using both real-time RT-PCR and ddPCR, and no significant differences were observed comparing samples taken with and without customers. Modelling average concentrations, using influx of customers' data and local epidemiological information, indicated low values (i.e. < 0.8 copies m
Identifiants
pubmed: 34599449
doi: 10.1007/s11356-021-16737-7
pii: 10.1007/s11356-021-16737-7
pmc: PMC8486635
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
13905-13916Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Adams WC (1993) Measurement of breathing rate and volume in routinely performed daily activities. Final report. Human Performance Laboratory, Physical Education Department, University of California, Davis. Human Performance Laboratory, Physical Education Department, University of California, Davis. Prepared for the California Air Resources Board, Contract No. A033-205, April 1993.
Aleya L, Gu W, Howard S (2021) Environmental factors and the epidemics of COVID-19. Environmental Science and Pollution Research. https://doi.org/10.1007/s11356-021-14721-9
Alteri C, Cento V, Antonello M, Colagrossi L, Merli M, Ughi N, Renica S, Matarazzo E, Di Ruscio F, Tartaglione L, Colombo J, Grimaldi C, Carta S, Nava A, Costabile V, Baiguera C, Campisi D, Fanti D, Vismara C et al (2020) Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients. PLoS ONE 15(9):e0236311. https://doi.org/10.1371/journal.pone.0236311
Asadi S, Bouvier N, Wexler AS, Ristenpart WD (2020) The coronavirus pandemic and aerosols: Does COVID-19 transmit via expiratory particles? Aerosol Science and Technology 54(6):635–638
doi: 10.1080/02786826.2020.1749229
Balachandar S, Zaleski S, Soldati A, Ahmadi G, Borouiba L (2020) Host-to-host airborne transmission as a multiphase problem for science-based social distance guidelines. International Journal of Multiphase Flow 132:103439
doi: 10.1016/j.ijmultiphaseflow.2020.103439
Bhagat RK, Wykes MSD, Dalziel SB, Linden PF (2020) Effects of ventilation on the indoor spread of COVID-19. Journal of Fluid Mechanics 903(F1)
Allen JG, Marr LC (2020) Recognizing and controlling airborne transmission of SARSCoV-2 in indoor environments. Indoor Air 30:557–558
doi: 10.1111/ina.12697
Belosi F, Conte M, Gianelle V, Santachiara G, Contini D (2021) On the concentration of SARS-CoV-2 in outdoor air and the interaction with pre-existing atmospheric particles. Environmental Research 193:110603
doi: 10.1016/j.envres.2020.110603
Borges JT, Nakada LY, Maniero MG, Guimarães JR (2021) SARS-CoV-2: a systematic review of indoor air sampling for virus detection. Environmental Science and Pollution Research. https://doi.org/10.1007/s11356-021-13001-w
Borouiba L (2020) Turbulent gas clouds and respiratory pathogen emissions, potential implications for reducing transmission of COVID-19. JAMA 323(18):1837–1838
Buonanno G, Stabile L, Morawska L (2020) Estimation of airborne viral emission: quanta emission rate of SARS-CoV-2 for infection risk assessment. Environment International 141:105794
doi: 10.1016/j.envint.2020.105794
Cheng VCC, Wong SC, Chan VWM, So SYC, Chen JHK, Yip CCY, Chan KH, Chu H, Chung TWH, Sridhar S, To, K.K.W, Chan JFW, Hung IFN, Ho PL, Yuen KY (2020) Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infection Control & Hospital Epidemiology 41(11):1258–1265
doi: 10.1017/ice.2020.282
Chia PY, Coleman KK, Tan YK, Ong SWX, Gum M, Lau SK, Lim XF, Lim AS, Sutjipto S, Lee PH, Son TT, Young BE, Milton DK, Gray GC, Schuster S, Barkham T, De PP, Vasoo S, Chan M et al (2020) Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nature Communications 11:2800
Chirizzi D, Conte M, Feltracco M, Dinoi A, Gregoris E, Barbaro E, La Bella G, Ciccarese G, La Salandra G, Gambaro A, Contini D (2021) SARS-CoV-2 concentrations and virus-laden aerosol size distributions in outdoor air in north and south of Italy. Environment International 146:106255
doi: 10.1016/j.envint.2020.106255
Contini D, Costabile F (2020) Does air pollution influence COVID-19 outbreaks? Atmosphere 11:377
doi: 10.3390/atmos11040377
Di Carlo P, Chiacchiaretta P, Sinjari B, Aruffo E, Stuppia L, De Laurenzi V, Di Tomo P, Pelusi L, Potenza F, Veronese A, Vecchiet J, Falasca K, Ucciferri C (2020) Air and surface measurements of SARS-CoV-2 inside a bus during normal operation. PLoS ONE 15(11):e0235943
doi: 10.1371/journal.pone.0235943
Domingo JL, Marquès M, Rovira J (2020) Influence of airborne transmission of SARS-CoV-2 in COVID-19 pandemic. A review. Environmental Research 188:109861
doi: 10.1016/j.envres.2020.109861
Klompas M, Baker MA, Rhee C (2020) Airborne transmission of SARS-CoV-2. Theoretical considerations and available evidence. JAMA 324(5):441–442
doi: 10.1001/jama.2020.12458
Dong L, Zhou J, Niu C, Wang Q, Pan Y, Sheng S, Wang X, Zhang Y, Yang J, Liu M, Zhao Y, Zhang X, Zhu T, Peng T, Xie J, Gao Y, Wang D, Dai X, Fang X (2021) Highly accurate and sensitive diagnostic detection of SARS-CoV-2 by digital PCR. Talanta 224:121726
doi: 10.1016/j.talanta.2020.121726
Dumont-Leblond N, Veillette M, Bhérer L, Boissoneault K, Mubareka S, Yip L, Dubuis ME, Longtin Y, Jouvet P, McGeer A, Duchaine C (2021) Positive no-touch surfaces and undetectable SARS-CoV-2 aerosols in long-term care facilities: an attempt to understand the contributing factors and the importance of timing in air sampling campaigns. American Journal of Infection Control. https://doi.org/10.1016/j.ajic.2021.02.004
Dunker S, Hornick T, Szczepankiewicz G, Maier M, Bastl M, Bumberger J, Treudler R, Liebert UG, Simon JC (2021) No SARS-CoV-2 detected in air samples (pollen and particulate matter) in Leipzig during the first spread. Science of the Total Environment 755:142881
doi: 10.1016/j.scitotenv.2020.142881
Escandón K, Rasmussen AL, Bogoch II, Murray EJ, Escandón K, Popescu SV, Kindrachuk J (2021) COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection.BMC Infectious Diseases 21, 710.
Faridi S, Niazi S, Sadeghi K, Naddafi K, Yavarian J, Shamsipour M, Jandaghi NZS, Sadeghniiat K, Nabizadeh R, Yunesian M, Momeniha F, Mokamel A, Hassanvand MS, Azad TM (2020) A field indoor air measurement of SARS-CoV-2 in the patient rooms of the largest hospital in Iran. Science of the Total Environment 725:138401
doi: 10.1016/j.scitotenv.2020.138401
Feng Y, Thierry M, Sperry T, Yi H (2020) Influence of wind and relative humidity on the social distancing effectiveness to prevent COVID-19 airborne transmission: a numerical study. Journal of Aerosol Science 147:105585
doi: 10.1016/j.jaerosci.2020.105585
Gammaitoni L, Nucci MC (1997) Using a mathematical model to evaluate the efficacy of TB ontrol measures. Emerging Infectious Diseases 3:335–342
doi: 10.3201/eid0303.970310
Ge X-Y, Pu Y, Liao C-H, Huang W-F, Zeng Q, Zhou H, Yi B, Wang A-I, Dou Q-Y, Zhou P-C, Chen H-L, Liu H-X, Xu D-M, Chen X, Huang X (2020) Evaluation of the exposure risk of SARS-CoV-2 in different hospital environment. Sustainable Cities and Society 61:102413
doi: 10.1016/j.scs.2020.102413
Hadei M, Mohebbi SR, Hopke PK, Shahsavani A, Bazazpour S, Alipour MR, Jafari AJ, Bandpey AM, Zali A, Yarahmadi M, Farhadi M, Rahmatinia M, Hasanzadeh V, Nazari SSH, Asadzadeh-Aghdaei H, Tanhaei M, Zali MR, Kermani M, Vaziri MH, Chobineh H (2021) Presence of SARS-CoV-2 in the air of public places and transportation. Atmospheric Pollution Research 12(3):302–306
doi: 10.1016/j.apr.2020.12.016
Hemati S, Mobini GR, Heidari M, Rahmani F, Babadi AS, Farhadkhani M, Nourmoradi H, Raeisi A, Ahmadi A, Khodabakhshi A, Sadeghi M, Bagheri M, Validi M, Taghipour S, Mohammadi-Moghadam F (2021) Simultaneous monitoring of SARS-CoV-2, bacteria, and fungi in indoor air of hospital: a study on Hajar Hospital in Shahrekord, Iran. Environ Sci Pollut Res 10:1–11. https://doi.org/10.1007/s11356-021-13628-9
doi: 10.1007/s11356-021-13628-9
Hu J, Lei C, Chen Z, Liu W, Hu X, Pei R, Hu J, Lei C, Chen Z, Liu W, Hu X, Pei R, Su Z, Deng F, Huang Y, Sun X, Cao J, Guan W (2020) Distribution of airborne SARS-CoV-2 and possible aerosol transmission in Wuhan hospitals, China. National Science Review 7:1865–1867
doi: 10.1093/nsr/nwaa250
Jin T, Li J, Yang J, Li J, Hong F, Long H, Deng Q, Qin Y, Jiang J, Zhou X, Song Q, Pan C, Luo P (2020) SARS-CoV-2 presented in the air of an intensive care unit (ICU). Sustainable Cities and Society 65:102446
doi: 10.1016/j.scs.2020.102446
Kayalar O, Arı A, Babuççu G, Konyalılar N, Doğan O, Can F, Şahin UA, Gaga EO, Kuzu SL, Arı PE, Odabaşı M, Taşdemir Y, Cindoruk SS, Esen F, Sakın E, Çalışkan B, Tecer LH, Fıçıcı M, Altın A et al (2021) Existence of SARS-CoV-2 RNA on ambient particulate matter samples: a nationwide study in Turkey. Sci. Total Environ. 789:147976
Lednicky JA, Lauzardo M, Fan ZH, Jutla A, Tilly TB, Gangwar M, Usmani M, Shankar SN, Mohamed K, Eiguren-Fernandez A, Stephenson CJ, Alam MM, Elbadry MA, Loeb JC, Subramaniam K, Waltzek TB, Cherabuddi K, Morris JG Jr, Wu CY (2020) Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients. International Journal of Infectious Diseases 100:476–482
doi: 10.1016/j.ijid.2020.09.025
Lelieveld J, Helleis F, Borrmann S, Cheng Y, Drewnick F, Haug G, Klimach T, Sciare J, Su H, Pöschl U (2020) Model calculations of aerosol transmission and infection risk of COVID-19 in indoor environments. International Journal of Environmental Research and Public Health 17:8114
doi: 10.3390/ijerph17218114
Linillos-Pradillo B, Rancan L, Ramiro ED, Vara E, Artíñano B, Arias J (2021) Determination of SARS-CoV-2 RNA in different particulate matter size fractions of outdoor air samples in Madrid during the lockdown. Environ. Res. 195:110863
doi: 10.1016/j.envres.2021.110863
Liu Y, Ning Z, Chen Y, Guo M, Liu Y, Gali NK et al (2020) Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals. Nature 582:557–560
doi: 10.1038/s41586-020-2271-3
Martano P (2020) Droplet fate in a cough puff. Atmosphere 11(8):841
doi: 10.3390/atmos11080841
Morawska L, Johnson GR, Ristovski ZD, Hargreaves M, Mengersen K, Corbett S, Chao CYH, Li Y, Katoshevski D (2009) Size distribution and sites of origin of droplets expelled from the human respiratory tract during expiratory activities. Journal of Aerosol Science 40:256–269
doi: 10.1016/j.jaerosci.2008.11.002
Morawska L, Cao J (2020) Airborne transmission of SARS-CoV-2: The world should face the reality. Environment International 139:105730
doi: 10.1016/j.envint.2020.105730
Moreno T, Pintó RM, Bosch A, Moreno N, Alastuey A, Minguillón MC, Anfruns-Estrada E, Guix S, Fuentes C, Buonanno G, Stabile L, Morawska L, Querol X (2021) Tracing surface and airborne SARS-CoV-2 RNA inside public buses and subway trains. Environment International 147:106326
doi: 10.1016/j.envint.2020.106326
Ong SWX, Tan YK, Chia PK, Lee TH, Ng OT, Wong MSY, Marimuthu K (2020) Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA 323(16):1610–1612
doi: 10.1001/jama.2020.3227
Pan M, Lednicky JA, Wu C-Y (2019) Collection, particle sizing and detection of airborne viruses. Journal of Applied Microbiology 127:1596
doi: 10.1111/jam.14278
Passos RG, Silveira MB, Abrahão JS (2021) Exploratory assessment of the occurrence of SARS-CoV-2 in aerosols in hospital facilities and public spaces of a metropolitan center in Brazil. Environmental Research 195:110808
doi: 10.1016/j.envres.2021.110808
Pintó RM, Costafreda MI, Bosch A (2009) Risk assessment in shellfish-borne outbreaks of hepatitis A. Applied Environmental Microbiology 75(23):7350–7355
doi: 10.1128/AEM.01177-09
Pivato A, Amoruso I, Formenton G, Di Maria F, Bonato T, Vanin S, Marion A, Baldovin T (2021) Evaluating the presence of SARS-CoV-2 RNA in the particulate matters during the peak of COVID-19 in Padua, northern Italy. Science of The Total Environment 784:147129
doi: 10.1016/j.scitotenv.2021.147129
Prather KA, Wang CC, Schooley RT (2020) Reducing transmission of SARS-COV-2. Science 368(6498):1422–1424
doi: 10.1126/science.abc6197
Ram K, Thakur RC, Singh DK, Kawamura K, Shimouchi A, Sekine Y, Nishimura H, Singh SK, Pavuluri CM, Singh RS, Tripathi SN (2021) Why airborne transmission hasn’t been conclusive in case of COVID-19? An atmospheric science perspective. Science of the Total Environment 773:145525
doi: 10.1016/j.scitotenv.2021.145525
Razzini K, Castrica M, Menchetti L, Maggi L, Negroni L, Orfeo NV, Pizzoccheri A, Stocco MS, Balzaretti CM (2020) SARS-CoV-2 RNA detection in the air and on surfaces in the COVID-19 ward of a hospital in Milan, Italy. Science of the Total Environment 742:140540
doi: 10.1016/j.scitotenv.2020.140540
Robotto A, Quaglino P, Lembo D, Morello M, Brizio E, Bardi L, Civra A (2021) SARS-CoV-2 and indoor/outdoor air samples: a methodological approach to have consistent and comparable results. Environmental Research 195:110847
doi: 10.1016/j.envres.2021.110847
Santarpia JL, Rivera DN, Herrera VL, Morwitzer MJ, Creager HM, Santarpia GW, Crown KK, Brett-Major DM, Schnaubelt ER, Broadhurst MJ, Lawler JV, Reid StP, Lowe JJ (2020). Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care. Sci Rep. 29, 10(1):12732.
Setti L, Passarini F, De Gennaro G, Barbieri P, Perrone MG, Borelli M, Palmisani J, Di Gilio A, Torboli V, Fontana F, Clemente L, Pallavicini A, Ruscio M, Piscitelli P, Miani A (2020) SARS-CoV-2 RNA found on particulate matter of Bergamo in Northern Italy: first evidence. Environmental Research 188:109754
doi: 10.1016/j.envres.2020.109754
Stern RA, Koutrakis P, Martins MAG, Lemos B, Down SE, Sunderland EM, Garshick E (2021) Characterization of hospital airborne SARS-CoV-2. Respiratory Research 22:73
doi: 10.1186/s12931-021-01637-8
Suo T, Liu X, Feng J, Guo M, Hu M, Guo D, Ullah H, Yang Y, Zhang Q, Wang X, Sajid M, Huang Z, Deng L, Chen T, Liu F, Xu K, Liu Y, Zhang Q, Liu Y et al (2020) ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens. Emerging Microbes & Infections 9(1):1259–1268
Tang JW, Bahnfleth WP, Bluyssen PM, Buonanno G, Jimenez JL, Kurnitski J, Li Y, Miller S, Sekhar C, Morawska L, Marr LC, Melikov AK, Nazaroff WW, Nielsen PV, Tellier R, Wargocki PI, Dancer SJ (2021) Dismantling myths on the airborne transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Journal of Hospital Infection 110:89–96
doi: 10.1016/j.jhin.2020.12.022
Vosoughi M, Karami C, Dargahi A, Jeddi F, Jalali KM, Hadisi A, Haghighi SB, Dogahe HP, Noorimotlagh Z, Mirzaee AS (2021) Investigation of SARS-CoV-2 in hospital indoor air of COVID-19 patients’ ward with impinger method. Environ Sci Pollut Res. https://doi.org/10.1007/s11356-021-14260-3
Xu, I., Cai, J., Li, S., He, Q., Zhu, S., 2021. Airborne infection risks of SARS-CoV-2 in U.S. Schools and impacts of different intervention strategies. Sustainable Cities and Society, 103188.
Yun H, Yang J, Seo JH, Sohn JR (2020) Methodology for sampling and detection of airborne coronavirus including SARS-CoV-2. Indoor and Built Environment. https://doi.org/10.1177/1420326X20980160