Effect of Apixaban Pretreatment on Alteplase-Induced Thrombolysis: An
alteplase
apixaban
clot
in vitro
stroke
thrombolysis
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
07
2021
accepted:
27
08
2021
entrez:
4
10
2021
pubmed:
5
10
2021
medline:
5
10
2021
Statut:
epublish
Résumé
Benefit of thrombolytic therapy in patients with acute stroke, who are on anticoagulant treatment, is not well addressed. The aim of this study was to investigate whether apixaban can modify the thrombolytic efficacy of alteplase
Identifiants
pubmed: 34603054
doi: 10.3389/fphar.2021.740930
pii: 740930
pmc: PMC8479181
doi:
Types de publication
Journal Article
Langues
eng
Pagination
740930Informations de copyright
Copyright © 2021 Thalerová, Pešková, Kittová, Gulati, Víteček, Kubala and Mikulík.
Déclaration de conflit d'intérêts
This study received funding from the Pfizer Inc. through a competitive grant from the BMS/Pfizer European Thrombosis Investigator Initiated Research Program (ERISTA). The funder was not involved in the study design, collection, analysis, interpretation of data and the writing of this article. The submission for publication was approved by the funder. All authors declare no other competing interests.
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