Photochemically derived 1-aminonorbornanes provide structurally unique succinate dehydrogenase inhibitors with


Journal

Cell reports. Physical science
ISSN: 2666-3864
Titre abrégé: Cell Rep Phys Sci
Pays: United States
ID NLM: 101769239

Informations de publication

Date de publication:
22 Sep 2021
Historique:
entrez: 4 10 2021
pubmed: 5 10 2021
medline: 5 10 2021
Statut: ppublish

Résumé

Agrochemical fungicidal leads have been prepared from photochemically derived 1-aminonorbornane building blocks. The unique 1-aminonorbornane core is generated via direct excitation of a Schiff base precursor, leveraging the

Identifiants

pubmed: 34604820
doi: 10.1016/j.xcrp.2021.100548
pmc: PMC8486155
mid: NIHMS1742839
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM127774
Pays : United States

Déclaration de conflit d'intérêts

DECLARATION OF INTERESTS Efforts related to this work are the subject of ongoing commercialization efforts, as supported by the University of Michigan Office of Technology Transfer. D.S. and C.R.J.S. are authors of provisional patent filings associated with this research.

Références

Fungal Biol. 2019 Aug;123(8):555-557
pubmed: 31345409
Science. 2014 Feb 28;343(6174):1239176
pubmed: 24578578
Angew Chem Int Ed Engl. 2019 Dec 19;58(52):19000-19006
pubmed: 31701606
Phytopathology. 2013 Sep;103(9):880-7
pubmed: 23593940
J Med Chem. 2009 Nov 12;52(21):6752-6
pubmed: 19827778
Chimia (Aarau). 2015;69(7-8):425-34
pubmed: 26507595
J Med Chem. 2014 Sep 11;57(17):7206-15
pubmed: 24856517
Mol Plant Pathol. 2012 May;13(4):414-30
pubmed: 22471698
Annu Rev Phytopathol. 2018 Aug 25;56:339-360
pubmed: 29958074
Chem Rev. 2016 Sep 14;116(17):9683-747
pubmed: 27120289
Fungal Biol. 2019 Aug;123(8):558-564
pubmed: 31345410
J Agric Food Chem. 2021 Apr 7;69(13):3965-3971
pubmed: 33779164
Nat Chem. 2018 Apr;10(4):383-394
pubmed: 29568051
J Med Chem. 2016 May 26;59(10):4443-58
pubmed: 26571338

Auteurs

Daryl Staveness (D)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

Mikaela Breunig (M)

Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA.

Viviana Ortiz (V)

Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA.

Hyunkyu Sang (H)

Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA.
Department of Integrative Food, Bioscience, and Biotechnology, Chonnam National University, Gwangju 61186, Korea.

James L Collins (JL)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

Rory C McAtee (RC)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

Martin I Chilvers (MI)

Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA.

Corey R J Stephenson (CRJ)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Lead contact.

Classifications MeSH