Functional nitrergic innervation of smooth muscle structures in the mucosa of pig lower urinary tract.


Journal

Cell and tissue research
ISSN: 1432-0878
Titre abrégé: Cell Tissue Res
Pays: Germany
ID NLM: 0417625

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 06 05 2021
accepted: 15 08 2021
pubmed: 5 10 2021
medline: 26 2 2022
entrez: 4 10 2021
Statut: ppublish

Résumé

Neurally released nitric oxide (NO) functions as an inhibitory neurotransmitter of urethral but not detrusor smooth muscles while relaxing bladder vasculature and muscularis mucosae (MM). Here, the distribution of nitrergic nerves was examined in the mucosa of pig lower urinary tract using immunohistochemistry, and their vasodilatory functions were studied by measuring arteriolar diameter changes. Properties of smooth muscle cells in the lamina propria (SMC-LP) of urethra and trigone were also investigated using florescence Ca

Identifiants

pubmed: 34604930
doi: 10.1007/s00441-021-03521-9
pii: 10.1007/s00441-021-03521-9
doi:

Substances chimiques

Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

513-531

Subventions

Organisme : Japan Society for Promotion of the Science
ID : 19K08426
Organisme : Japan Society for Promotion of the Science
ID : 17K11187
Organisme : Japan Society for Promotion of the Science
ID : 20K09564

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Retsu Mitsui (R)

Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. mitsui@med.nagoya-cu.ac.jp.

Yota Chikada (Y)

Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Keiji Arai (K)

Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Hikaru Hashitani (H)

Department of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

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Classifications MeSH