NAP1051, a Lipoxin A4 Biomimetic Analogue, Demonstrates Antitumor Activity Against the Tumor Microenvironment.
Journal
Molecular cancer therapeutics
ISSN: 1538-8514
Titre abrégé: Mol Cancer Ther
Pays: United States
ID NLM: 101132535
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
08
05
2021
revised:
26
07
2021
accepted:
27
09
2021
pubmed:
6
10
2021
medline:
26
3
2022
entrez:
5
10
2021
Statut:
ppublish
Résumé
Resolving tumor-associated inflammation in the tumor microenvironment (TME) may promote antitumor effects. Lipoxin A4 (LXA4) is a short-lived endogenous bioactive lipid with potent anti-inflammatory and pro-resolving properties. Here, a biomimetic of LXA4, NAP1051, was shown to have LXA4-like
Identifiants
pubmed: 34607931
pii: 1535-7163.MCT-21-0414
doi: 10.1158/1535-7163.MCT-21-0414
doi:
Substances chimiques
Lipoxins
0
lipoxin A4
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2384-2397Informations de copyright
©2021 American Association for Cancer Research.
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