Renal involvement in COVID-19: focus on kidney transplant sector.
COVID-19
Immunosuppressant
Kidney transplantation
SARS-CoV-2
Journal
Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
15
07
2021
accepted:
22
09
2021
pubmed:
7
10
2021
medline:
27
11
2021
entrez:
6
10
2021
Statut:
ppublish
Résumé
Kidney transplant recipients and patients on the waiting list for kidney transplant who acquire SARS-CoV-2 infection are at serious risk of developing severe COVID-19, with an increased risk of mortality for the their immunosuppressive state; other risk factors for mortality have been identified in some comorbidities such as obesity, diabetes, asthma and chronic lung disease. The COVID-19 pandemic has led to a sharp reduction in kidney transplants in most countries, mainly due to the concern of patients on the waiting list for their potential increased susceptibility to acquire SARS-CoV-2 infection in healthcare facilities and for the difficulties of transplant centers to ensure full activity as hospitals have had to focus most of their attention on COVID-19 patients. Indeed, while the infection curve continued its exponential rise, there was a vertical decline in kidney donation/transplant activity. This review article focuses on the damage induced by SARS-CoV-2 infection on kidney and on the adverse effect of this pandemic on the entire kidney transplant sector.
Identifiants
pubmed: 34611792
doi: 10.1007/s15010-021-01706-6
pii: 10.1007/s15010-021-01706-6
pmc: PMC8491762
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1265-1275Informations de copyright
© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.
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