Muscle synergy structure and gait patterns in children with spastic cerebral palsy.
Journal
Developmental medicine and child neurology
ISSN: 1469-8749
Titre abrégé: Dev Med Child Neurol
Pays: England
ID NLM: 0006761
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
02
08
2021
received:
30
10
2020
accepted:
01
09
2021
pubmed:
7
10
2021
medline:
28
4
2022
entrez:
6
10
2021
Statut:
ppublish
Résumé
To determine if muscle synergy structure (activations and weights) differs between gait patterns in children with spastic cerebral palsy (CP). In this cross-sectional study, we classified 188 children with unilateral (n=82) or bilateral (n=106) spastic CP (mean age: 9y 5mo, SD: 4y 3mo, range: 3y 9mo-17y 7mo; 75 females; Gross Motor Function Classification System [GMFCS] level I: 106, GMFCS level II: 55, GMFCS level III: 27) into a minor deviations (n=34), drop foot (n=16), genu recurvatum (n=26), apparent equinus (n=53), crouch (n=39), and jump gait pattern (n=20). Surface electromyography recordings from eight lower limb muscles of the most affected side were used to calculate synergies with weighted non-negative matrix factorization. We compared synergy activations and weights between the patterns. Synergy structure was similar between gait patterns, although weights differed in the more impaired children (crouch and jump gait) when compared to the other patterns. Variability in synergy structure between participants was high. The similarity in synergy structure between gait patterns suggests a generic motor control strategy to compensate for the brain lesion. However, the differences in weights and high variability between participants indicate that this generic motor control strategy might be individualized and dependent on impairment level.
Identifiants
pubmed: 34614213
doi: 10.1111/dmcn.15068
pmc: PMC9292989
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
462-468Subventions
Organisme : NINDS NIH HHS
ID : R01 NS091056
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.
Références
Gait Posture. 2019 Mar;69:209-223
pubmed: 30851621
PLoS One. 2017 Jan 12;12(1):e0169834
pubmed: 28081229
Gait Posture. 2019 Jan;67:290-295
pubmed: 30396059
Dev Med Child Neurol. 2009 Aug;51(8):607-14
pubmed: 19220390
Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9604-9612
pubmed: 32284405
J Neurophysiol. 2019 May 1;121(5):1680-1691
pubmed: 30892974
J Bone Joint Surg Br. 2004 Mar;86(2):251-8
pubmed: 15046442
Bioinformatics. 2007 Jun 15;23(12):1495-502
pubmed: 17483501
Front Hum Neurosci. 2020 Jul 09;14:275
pubmed: 32733223
Gait Posture. 2016 Mar;45:127-32
pubmed: 26979894
Front Hum Neurosci. 2017 Mar 17;11:103
pubmed: 28367118
J Pediatr Orthop. 2001 Nov-Dec;21(6):784-9
pubmed: 11675555
Neuron. 2015 Apr 8;86(1):38-54
pubmed: 25856485
Brain Struct Funct. 2021 Jan;226(1):69-91
pubmed: 33180142
Dev Med Child Neurol. 2015 Dec;57(12):1176-82
pubmed: 26084733
J Neurophysiol. 2005 Jan;93(1):609-13
pubmed: 15342720
J Neurophysiol. 2001 Feb;85(2):605-19
pubmed: 11160497
Science. 2011 Nov 18;334(6058):997-9
pubmed: 22096202
J Electromyogr Kinesiol. 2000 Oct;10(5):361-74
pubmed: 11018445
Dev Med Child Neurol. 2014 Jun;56(6):522-8
pubmed: 24359183
Neuroimage. 2019 Oct 1;199:30-37
pubmed: 31121297
Front Hum Neurosci. 2014 May 23;8:335
pubmed: 24904375
J Neuroeng Rehabil. 2019 Mar 29;16(1):46
pubmed: 30925882
Dev Med Child Neurol. 2010 Mar;52(3):264-9
pubmed: 20089048