Extremes of cerebral blood flow during hypercapnic squat-stand maneuvers.


Journal

Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800

Informations de publication

Date de publication:
10 2021
Historique:
revised: 04 08 2021
received: 18 05 2021
accepted: 09 08 2021
entrez: 7 10 2021
pubmed: 8 10 2021
medline: 11 3 2022
Statut: ppublish

Résumé

Squat-stand maneuvers (SSMs) are a popular method of inducing blood pressure (BP) oscillations to reliably assess dynamic cerebral autoregulation (dCA), but their effects on the cerebral circulation remain controversial. We designed a protocol whereby participants would perform SSMs under hypercapnic conditions. Alarmingly high values of cerebral blood flow velocity (CBFV) were recorded, leading to early study termination after the recruitment of a single participant. One healthy subject underwent recordings at rest (5 min sitting, 5 min standing) and during two SSMs (fixed and random frequency). Two sets of recordings were collected; one while breathing room air, one while breathing 5% CO

Identifiants

pubmed: 34617685
doi: 10.14814/phy2.15021
pmc: PMC8495794
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

e15021

Informations de copyright

© 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.

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Auteurs

Samuel C Barnes (SC)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Victoria J Haunton (VJ)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.

Lucy Beishon (L)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Osian Llwyd (O)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Thompson G Robinson (TG)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.

Ronney B Panerai (RB)

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.

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Classifications MeSH