Microsurgical clipping versus newer endovascular techniques in treatment of unruptured anterior communicating artery-complex aneurysms: a meta-analysis and systematic review.


Journal

Neurosurgical review
ISSN: 1437-2320
Titre abrégé: Neurosurg Rev
Pays: Germany
ID NLM: 7908181

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 27 06 2021
accepted: 10 09 2021
revised: 26 08 2021
pubmed: 9 10 2021
medline: 6 4 2022
entrez: 8 10 2021
Statut: ppublish

Résumé

The aim of this study is to compare occlusion rate, complication rate, and clinical outcome of microsurgical clipping (MC) and advanced endovascular techniques (EVT) in unruptured anterior communicating artery-complex aneurysms (ACoCAs). We reviewed the scientific literature reporting occlusion rate, time of occlusion assessment, and clinical outcome of MC and EVT in patients with unruptured ACoCAs, from January 2009 to December 2019. We included in our analysis 25 studies and 872 patients with unruptured ACoCAs (434 treated with endovascular techniques and 438 with MC). Ninety-three (10.7%), 320 (36.7%), 21 (2.4%), and 438 (50.2%) were treated with flow diverter (FD), stent-assisted coiling (SAC), endosaccular devices (ES), and microsurgical clipping (MC) respectively. FD, SAC, ES, and MC subgroups presented minor complications in 11.8%, 3.8%, 14.3%, and 7.1% of cases (p=.016), and major complications in 3.2%, 4.4%, 0%, and 7.1% (p=.136) of patients. A total occlusion rate post-treatment has been achieved in 4.3%, 87.1%, 47.6%, and 98.2% of cases (p=.000), while at 12 months' follow-up in 50%, 66%, 83.3%, and 80% of patients (p=.001). FD, SAC, ES, and MC subgroups had a good clinical outcome at 12 months in 93.5%, 90.5%, 100%, and 67.8% of cases. MC is associated with higher post-treatment total occlusion rate, but higher complication and lower good clinical outcome rates. EVT are promising in treating unruptured anterior cerebral artery aneurysms with high margin of safety and good clinical outcome, despite the lower total occlusion rate.

Identifiants

pubmed: 34622332
doi: 10.1007/s10143-021-01647-6
pii: 10.1007/s10143-021-01647-6
doi:

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1089-1100

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

F Diana (F)

Department of Neuroradiology, A.O.U. San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy.

A Pesce (A)

Department of Neurosurgery, Ospedale Santa Maria Goretti, Latina, Italy.

G Toccaceli (G)

Department of Emergency Neurosurgery, Ospedale Civile "Santo Spirito" di Pescara, Pescara, Italy. toccaceli.giada@gmail.com.

V Muralidharan (V)

Division of Neurosurgery, Panimalar Medical College Hospital and Research Institute, Chennai, India.

E Raz (E)

Department of Radiology, NYU Langone Health, New York, NY, USA.

M Miscusi (M)

Operative Unit of Neurosurgery, AOSA, Department of NESMOS, Sapienza, Rome, Italy.

A Raco (A)

Operative Unit of Neurosurgery, AOSA, Department of NESMOS, Sapienza, Rome, Italy.

P Missori (P)

Department of Human Neurosciences, Neurosurgery, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.

S Peschillo (S)

Department of Surgical Medical Sciences and Advanced Technologies "G.F. Ingrassia" - Endovascular Neurosurgery, University of Catania, Catania, Italy.
Pia Fondazione Cardinale Giovanni Panico Hospital, Tricase, LE, Italy.

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